Department of Hematology-Oncology, UCSF Benioff Children's Hospital Oakland, Oakland, California.
Department of Hematology-Oncology, Children's Hospital of Los Angeles, Los Angeles, California.
Pediatr Blood Cancer. 2019 Jul;66(7):e27753. doi: 10.1002/pbc.27753. Epub 2019 Apr 11.
Ovarian angiosarcoma is a rare and aggressive vascular tumor, which has a 5-year overall survival of less than 30% for patients with nonmetastatic disease and almost certain death within 1 year for those with metastasis. Here, we briefly review historical approaches to therapy and present a long-term survivor in the case of an 11-year-old female with metastatic ovarian angiosarcoma. This is the second reported case to utilize heated intraperitoneal chemotherapy in the treatment of this disease. Our patient is currently alive and well 3 years after initial diagnosis, significantly longer than any reported case of advanced-stage ovarian angiosarcoma.
卵巢血管肉瘤是一种罕见且侵袭性的血管肿瘤，对于非转移性疾病患者，其 5 年总生存率不足 30%，而对于转移性疾病患者，几乎在 1 年内死亡。在此，我们简要回顾历史治疗方法，并报告一例患有转移性卵巢血管肉瘤的 11 岁女性长期生存病例。这是第二例报道的在该疾病治疗中应用腹腔热灌注化疗的病例。我们的患者在初始诊断后 3 年仍然存活且状况良好，明显长于任何报道的晚期卵巢血管肉瘤病例。
