1 Cardiovascular Prevention and Rehabilitation (EPIC) Center, Montreal Heart Institute and University of Montreal, Montreal, QC, Canada.
2 Research Center, Montreal Heart Institute and University of Montreal, Montreal, QC, Canada.
Clin Rehabil. 2019 Aug;33(8):1320-1330. doi: 10.1177/0269215519840388. Epub 2019 Apr 12.
To compare the effects of high-intensity interval training versus moderate-intensity continuous training on risk markers of arrhythmic death in patients who recently suffered from an acute coronary syndrome.
Double-blind (patient and evaluator) randomized controlled trial.
Cardiovascular Prevention and Rehabilitation Centre (EPIC Centre) of the Montreal Heart Institute, Montreal, Canada.
A total of 43 patients were randomized following an acute coronary syndrome.
Patients were assigned to either high-intensity interval training (n = 18) or isocaloric moderate-intensity continuous training (n = 19), three times a week for a total of 36 sessions.
Heart rate recovery for 5 minutes, heart rate variability for 24 hours, occurrence of ventricular arrhythmias, and QT dispersion were measured before and after the 36 sessions of training.
Among the 43 patients randomized, 6 participants in the high-intensity interval training group stopped training for reasons unrelated to exercise training and were excluded from the analyses. Heart rate recovery improved solely in the high-intensity interval training group, particularly at the end of recovery period ( < 0.05). There were no differences in heart rate variability, occurrence of ventricular arrhythmias, or QT dispersion parameters between the groups at study end.
Despite the lack of power to detect any large difference between the two interventions with respect to risk markers of arrhythmic death, high-intensity interval training appears safe and may be more effective at improving heart rate recovery relative to moderate-intensity continuous training in our patients following acute coronary syndrome.
比较高强度间歇训练与中等强度持续训练对近期急性冠状动脉综合征患者心律失常性死亡风险标志物的影响。
双盲（患者和评估者）随机对照试验。
加拿大蒙特利尔心脏研究所心血管预防和康复中心（EPIC 中心）。
共有 43 例患者在急性冠状动脉综合征后随机分组。
患者被分配到高强度间歇训练组（n = 18）或等热量中等强度持续训练组（n = 19），每周 3 次，共 36 次。
5 分钟内心率恢复、24 小时内心率变异性、室性心律失常发生情况和 QT 离散度，在 36 次训练前后进行测量。
在随机分组的 43 例患者中，高强度间歇训练组有 6 例患者因与运动训练无关的原因停止训练，这些患者被排除在分析之外。仅在高强度间歇训练组中，心率恢复得到改善，特别是在恢复期结束时（<0.05）。两组在研究结束时的心率变异性、室性心律失常发生情况或 QT 离散度参数均无差异。
尽管缺乏针对两种干预措施在心律失常性死亡风险标志物方面的任何大差异进行检测的效力，但高强度间歇训练在急性冠状动脉综合征后患者中似乎是安全的，并且可能比中等强度持续训练更有效地改善心率恢复。
