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西班牙初级保健机构中勃起功能障碍的患病率及其与心血管危险因素和心血管疾病的关联。SIMETAP-ED研究。

Prevalence of erectile dysfunction in Spanish primary care setting and its association with cardiovascular risk factors and cardiovascular diseases. SIMETAP-ED study.

作者信息

Ruiz-García Antonio, Arranz-Martínez Ezequiel, Cabrera-Vélez Roberto, Palacios-Martínez David, Rivera-Teijido Montserrat, García-Álvarez Juan Carlos, Morales-Cobos Luis Enrique, Moreno-Fernández Juan Carlos, García-Fernández María Eugenia, Peña-Antón Nuria, Díez-Pérez Maria Cruz, Montero-Costa Alejandra, Lorenzo-Borda María Soledad, García-Granado María Dolores, Casaseca-Calvo Teresa Fátima, Cique-Herráinz Juan A, García-Villasur María Paloma, Marañón-Henrich Nuria, Zarzuelo-Martín Nieves, Baltuille-Aller María Camino, Arribas-Álvaro Pilar, Macho-Barrio Ana Isabel, Ribot-Catalá Carlos, Capitán-Caldas Mercedes, Ciria-de-Pablo Cristina, Sanz-Velasco Carmelina, Vargas-Machuca-Cabañero Concepción, Simonaggio-Stancampiano Paula, Cabello-Igual María Pilar, Sarria-Sánchez María Teresa

机构信息

University Health Center Pinto, Lipids and Cardiovascular Prevention Unit, Madrid Health Service, C/ Marqués, s/n, 28320 Pinto-Madrid, Spain.

Health Center San Blas, Madrid Health Service, C/ San Blas, 24A, 28981 Parla-Madrid, Spain.

出版信息

Clin Investig Arterioscler. 2019 May-Jun;31(3):101-110. doi: 10.1016/j.arteri.2019.01.002. Epub 2019 Apr 9.

DOI:10.1016/j.arteri.2019.01.002
PMID:30979438
Abstract

INTRODUCTION

Few studies conducted in primary care setting report about age-adjusted prevalence rates of erectile dysfunction (ED). Aims of SIMETAP-ED study were to determine crude and age-adjusted prevalence rates of ED diagnosis, to compare these rates with other similar studies, and to compare prevalence rates of cardiovascular risk factors (CVRF), cardiovascular diseases (CVD), metabolic diseases and chronic kidney disease (CKD) between populations with and without ED.

METHODS

Cross-sectional observational study conducted in primary care setting. Population-based random sample: 2934 adult men. Response rate: 66%. A clinical interview was conducted to diagnose ED using a question derived from ED definition. The medical records of patients were reviewed to identify their CVRF and diseases associated with ED. The age-adjustments were standardized to Spanish population.

RESULTS

The prevalence rates of metabolic diseases, CVD, CVRF, and CKD in population with ED were higher than population without ED, highlighting the CVD. The crude prevalence of ED was 17.2% (95% confidence interval: 15.8-18.6). The age-adjusted prevalence rates of ED were 0.71% in men under 40 years, 12.4% in men over 18 years, 10.8% in men aged 40-69 years, 18.9% in men over 40 years, and 48.6% in men over 70 years.

CONCLUSIONS

SIMETAP-ED study showed association of ED with metabolic diseases, CKD, CVRF, and highlighting CVD. The age-adjusted prevalence of ED was 12.4% in adult men, 19% in men over 40 years, and almost 50% in men over 70 years.

摘要

引言

在初级保健机构开展的研究中,很少有报告提及勃起功能障碍(ED)的年龄调整患病率。SIMETAP-ED研究的目的是确定ED诊断的粗患病率和年龄调整患病率,将这些患病率与其他类似研究进行比较,并比较有ED和无ED人群中心血管危险因素(CVRF)、心血管疾病(CVD)、代谢疾病及慢性肾脏病(CKD)的患病率。

方法

在初级保健机构进行的横断面观察性研究。基于人群的随机样本:2934名成年男性。应答率:66%。采用源自ED定义的问题进行临床访谈以诊断ED。查阅患者的病历以确定其CVRF及与ED相关的疾病。年龄调整采用西班牙人群的标准。

结果

有ED人群中代谢疾病、CVD、CVRF及CKD的患病率高于无ED人群,其中CVD尤为突出。ED的粗患病率为17.2%(95%置信区间:15.8 - 18.6)。40岁以下男性的年龄调整患病率为0.71%,18岁以上男性为12.4%,40 - 69岁男性为10.8%,40岁以上男性为18.9%,70岁以上男性为48.6%。

结论

SIMETAP-ED研究显示ED与代谢疾病、CKD、CVRF相关,且CVD尤为突出。成年男性ED的年龄调整患病率为12.4%,40岁以上男性为19%,70岁以上男性近50%。

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