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《2型糖尿病降糖治疗指南(2019年更新版)》

[Antihyperglycemic treatment guidelines for diabetes mellitus type 2 (Update 2019)].

作者信息

Clodi Martin, Abrahamian Heidemarie, Brath Helmut, Brix Johanna, Drexel Heinz, Fasching Peter, Föger Bernhard, Francesconi Claudia, Fröhlich-Reiterer Elke, Harreiter Jürgen, Hofer Sabine E, Hoppichler Friedrich, Huber Joakim, Kaser Susanne, Kautzky-Willer Alexandra, Lechleitner Monika, Ludvik Bernhard, Luger Anton, Mader Julia K, Paulweber Bernhard, Pieber Thomas, Prager Rudolf, Rami-Merhar Birgit, Resl Michael, Riedl Michaela, Roden Michael, Saely Christoph H, Schelkshorn Christian, Schernthaner Guntram, Sourij Harald, Stechemesser Lars, Stingl Harald, Toplak Hermann, Wascher Thomas C, Weitgasser Raimund, Winhofer-Stöckl Yvonne, Zlamal-Fortunat Sandra

机构信息

ICMR - Institute for Cardiovascular and Metabolic Research, Johannes Kepler Universität Linz, 4040, Linz, Österreich.

Abteilung für Innere Medizin mit Diabetologie, Gastroenterologie und Hepatologie, Rheumatologie und Intensivmedizin, Konventhospital der Barmherzigen Brüder Linz, Seilerstätte 2, 4021, Linz, Österreich.

出版信息

Wien Klin Wochenschr. 2019 May;131(Suppl 1):27-38. doi: 10.1007/s00508-019-1471-z.

DOI:10.1007/s00508-019-1471-z
PMID:30980148
Abstract

Hyperglycemia significantly contributes to complications in patients with diabetes mellitus. While lifestyle interventions remain cornerstones of disease prevention and treatment, most patients with type 2 diabetes will eventually require pharmacotherapy for glycemic control. The definition of individual targets regarding optimal therapeutic efficacy and safety as well as cardiovascular effects is of great importance. In this guideline we present the most current evidence-based best clinical practice data for healthcare professionals.

摘要

高血糖显著促成糖尿病患者的并发症。虽然生活方式干预仍然是疾病预防和治疗的基石,但大多数2型糖尿病患者最终将需要药物治疗来控制血糖。关于最佳治疗效果、安全性以及心血管效应的个体目标的定义非常重要。在本指南中,我们为医疗保健专业人员提供了最新的循证最佳临床实践数据。

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[Antihyperglycemic treatment guidelines for diabetes mellitus type 2 (Update 2019)].《2型糖尿病降糖治疗指南(2019年更新版)》
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[Antihyperglycemic treatment guidelines for diabetes mellitus type 2 (Update 2023)].[2型糖尿病降糖治疗指南(2023年更新版)]
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[Antihyperglycemic treatment guidelines for diabetes mellitus type 2].[2型糖尿病降糖治疗指南]
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[Antihyperglycemic Treatment Guidelines for diabetes mellitus type 2].[2型糖尿病抗高血糖治疗指南]
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Current antihyperglycemic treatment guidelines and algorithms for patients with type 2 diabetes mellitus.现行 2 型糖尿病患者抗高血糖治疗指南和算法。
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[Guidelines for the management of diabetes mellitus type 2].[2型糖尿病管理指南]
Semergen. 2014 Sep;40 Suppl 4:11-8. doi: 10.1016/S1138-3593(14)74392-8.
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Treating hyperglycemia in type 2 diabetes: new goals and strategies.治疗2型糖尿病中的高血糖:新目标与策略。
Cleve Clin J Med. 2002 Oct;69(10):809-20. doi: 10.3949/ccjm.69.10.809.
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Nutr Metab Cardiovasc Dis. 2009 Nov;19(9):593-5. doi: 10.1016/j.numecd.2009.08.009.
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So Many Antihyperglycemics: How to Choose? A Practical Approach.如此多的抗高血糖药物:如何选择?一种实用方法。
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Glycemic Control Assessed by Intermittently Scanned Glucose Monitoring in Type 1 Diabetes during the COVID-19 Pandemic in Austria.在 COVID-19 大流行期间奥地利 1 型糖尿病患者通过间歇性扫描葡萄糖监测评估血糖控制情况。
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[Diabetic neuropathy and diabetic foot syndrome (update 2023)].

本文引用的文献

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Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes.达格列净与 2 型糖尿病患者的心血管结局
N Engl J Med. 2019 Jan 24;380(4):347-357. doi: 10.1056/NEJMoa1812389. Epub 2018 Nov 10.
2
Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).2018 年美国糖尿病协会(ADA)和欧洲糖尿病研究协会(EASD)的共识报告:2 型糖尿病患者高血糖的管理。
Diabetologia. 2018 Dec;61(12):2461-2498. doi: 10.1007/s00125-018-4729-5.
3
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes.
[糖尿病性神经病变与糖尿病足综合征(2023年更新)]
Wien Klin Wochenschr. 2023 Jan;135(Suppl 1):164-181. doi: 10.1007/s00508-023-02167-7. Epub 2023 Apr 20.
4
Lifestyle Parameters in Patients with Diabetes Mellitus and in the General Adult Population-Trends over Five Years: Results of the Austrian National Health Interview Series.糖尿病患者和普通成年人群的生活方式参数:五年趋势:奥地利国家健康访谈系列研究结果。
Int J Environ Res Public Health. 2021 Sep 21;18(18):9910. doi: 10.3390/ijerph18189910.
5
Risk factors for diabetic foot complications among patients with type 2 diabetes in Austria-A registry-based retrospective cohort study.奥地利基于注册的回顾性队列研究:2 型糖尿病患者糖尿病足并发症的危险因素。
Endocrinol Diabetes Metab. 2021 Oct;4(4):e00286. doi: 10.1002/edm2.286. Epub 2021 Jul 13.
6
Diabetic foot complications-lessons learned from real-world data derived from a specialized Austrian hospital.糖尿病足并发症——从奥地利一家专科医院的真实世界数据中汲取的经验教训
Wien Klin Wochenschr. 2022 Jan;134(1-2):7-17. doi: 10.1007/s00508-021-01864-5. Epub 2021 May 3.
7
Combined exenatide and dapagliflozin has no additive effects on reduction of hepatocellular lipids despite better glycaemic control in patients with type 2 diabetes mellitus treated with metformin: EXENDA, a 24-week, prospective, randomized, placebo-controlled pilot trial.二甲双胍治疗的 2 型糖尿病患者中,尽管血糖控制更好,但合用艾塞那肽和达格列净对降低肝细胞脂质没有额外作用:EXENDA,一项 24 周前瞻性随机安慰剂对照先导试验。
Diabetes Obes Metab. 2021 May;23(5):1129-1139. doi: 10.1111/dom.14319. Epub 2021 Feb 10.
8
Long-term trends in the prescription of antidiabetic drugs: real-world evidence from the Diabetes Registry Tyrol 2012-2018.抗糖尿病药物处方的长期趋势:来自蒂罗尔糖尿病登记处2012 - 2018年的真实世界证据。
BMJ Open Diabetes Res Care. 2020 Sep;8(1). doi: 10.1136/bmjdrc-2020-001279.
卡格列净与2型糖尿病患者的心血管及肾脏事件
N Engl J Med. 2017 Nov 23;377(21):2099. doi: 10.1056/NEJMc1712572.
4
Safety of Degludec versus Glargine in Type 2 Diabetes.德谷胰岛素与甘精胰岛素治疗2型糖尿病的安全性比较
N Engl J Med. 2017 Nov 16;377(20):1995-1996. doi: 10.1056/NEJMc1712575.
5
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Lancet Diabetes Endocrinol. 2017 Nov;5(11):877-886. doi: 10.1016/S2213-8587(17)30309-1. Epub 2017 Sep 13.
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Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial.吡格列酮与磺脲类药物联合治疗二甲双胍控制不佳的 2 型糖尿病患者心血管事件发生率的影响(TOSCA.IT):一项随机、多中心试验。
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N Engl J Med. 2017 Mar 2;376(9):891-2. doi: 10.1056/NEJMc1615712.
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Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes.恩格列净与 2 型糖尿病患者的肾脏疾病进展。
N Engl J Med. 2016 Jul 28;375(4):323-34. doi: 10.1056/NEJMoa1515920. Epub 2016 Jun 14.
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Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes.利拉鲁肽与2型糖尿病患者的心血管结局
N Engl J Med. 2016 Jul 28;375(4):311-22. doi: 10.1056/NEJMoa1603827. Epub 2016 Jun 13.
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Pioglitazone after Ischemic Stroke or Transient Ischemic Attack.缺血性中风或短暂性脑缺血发作后的吡格列酮
N Engl J Med. 2016 Apr 7;374(14):1321-31. doi: 10.1056/NEJMoa1506930. Epub 2016 Feb 17.