Ochsner Diabetes Clinical Research Unit, Department of Endocrinology, Diabetes and Metabolism, Ochsner Medical Center, New Orleans, Louisiana 70121, USA.
Am J Med. 2010 Mar;123(3 Suppl):S12-8. doi: 10.1016/j.amjmed.2009.12.005.
Type 2 diabetes mellitus and obesity are associated with increased cardiovascular risk. While lifestyle interventions such as medical nutrition therapy and appropriately prescribed physical activity remain cornerstones of disease prevention and treatment, most patients with type 2 diabetes will eventually require pharmacotherapy for glycemic control. Fortunately, many of these patients are able to achieve desired glycemic targets with the use of currently available antihyperglycemic agents. Both not-for-profit disease-specific organizations and healthcare specialty societies have provided guidance about the appropriate selection of these therapies. Type 2 diabetes treatment guidelines and algorithms have been developed, taking into account a combination of evidence-based information and expert opinions, with various groups offering diverse glucose goals and approaches to hyperglycemia management. Virtually all recognize that type 2 diabetes is a multifaceted disease, necessitating an integrated yet individualized approach to patient care.
2 型糖尿病和肥胖与心血管风险增加相关。虽然生活方式干预，如医学营养治疗和适当规定的身体活动，仍然是疾病预防和治疗的基石，但大多数 2 型糖尿病患者最终将需要药物治疗来控制血糖。幸运的是，许多这些患者能够通过使用现有的抗高血糖药物来达到理想的血糖目标。非营利性的特定疾病组织和医疗保健专业协会都提供了关于这些治疗方法的适当选择的指导。已经制定了 2 型糖尿病治疗指南和算法，考虑到基于证据的信息和专家意见的组合，不同的团体提供了不同的血糖目标和高血糖管理方法。几乎所有人都认识到，2 型糖尿病是一种多方面的疾病，需要采取综合但个体化的方法来进行患者护理。
