School of Dentistry, Universidade Franciscana, Santa Maria, RS, Brazil.
Master's Degree in Health and Life Sciences, Universidade Franciscana, Silva Jardim, 1175 - Centro, Santa Maria, RS, 97010-491, Brazil.
Support Care Cancer. 2020 Jan;28(1):65-71. doi: 10.1007/s00520-019-04792-3. Epub 2019 Apr 13.
The aim of the present study was to evaluate oral health-related quality of life (OHRQoL) among breast cancer survivors and identify possible factors associated with the outcome.
A cross-sectional study was conducted with 151 women in follow-up at a hospital after treatment for breast cancer. Data were collected on socio-demographic characteristics, general health, and breast cancer. Clinical examinations were performed to determine caries experience using the decayed, missing, and filled teeth (DMFT) index. The Oral Health Impact Profile (OHIP-14) questionnaire was administered for the assessment of OHRQoL. Logistic regression analysis was performed to identify associated factors after adjustments for confounding variables.
The mean OHIP-14 score was 12.8 (SD 10.92). The prevalence of negative impact was 58.9%. A negative impact was associated with depression, the diagnosis of breast cancer, chemotherapy, number of restored teeth, and xerostomia (p < 0.05). In the adjusted analysis, only the oral variables remained significantly associated with the outcome.
A greater number of restored teeth and xerostomia exert a negative impact on the OHRQoL of women who have survived breast cancer, which suggests the need for special attention to the oral health of this population.
本研究旨在评估乳腺癌幸存者的口腔健康相关生活质量(OHRQoL),并确定与结果相关的可能因素。
采用横断面研究方法,对 151 名在医院接受乳腺癌治疗后随访的女性进行研究。收集社会人口统计学特征、一般健康状况和乳腺癌等数据。进行临床检查,使用龋齿、缺失和补牙(DMFT)指数确定龋齿经历。使用口腔健康影响简表(OHIP-14)问卷评估 OHRQoL。进行逻辑回归分析,在调整混杂变量后确定相关因素。
OHIP-14 评分的平均值为 12.8(SD 10.92)。负面影响的患病率为 58.9%。负面影响与抑郁、乳腺癌诊断、化疗、修复牙齿数量和口干有关(p<0.05)。在调整分析中,只有口腔变量与结果仍有显著相关性。
更多的修复牙齿和口干对乳腺癌存活女性的 OHRQoL 产生负面影响,这表明需要特别关注该人群的口腔健康。