Zeerak Sumaya, Godse Kiran, Kumar Sujit
Department of Dermatology, Sub-District Hospital, Pampore, Srinagar, Jammu and Kashmir, India.
Department of Dermatology, Dr. D.Y. Patil School of Medicine, Mumbai, Maharashtra, India.
Indian J Dermatol. 2019 Mar-Apr;64(2):112-114. doi: 10.4103/ijd.IJD_325_17.
Antihistamines are one of the commonly prescribed groups of drugs for allergic disorders and pruritus. They are broadly grouped into two generations, the second-generation ones being more effective and with less side effects. The family physicians frequently use antihistamines as patients contact them initially for their problem. It will be interesting to know the mode of selection of antihistamines by them.
The study was carried out on a sample of 100 family physicians. Primary data were collected from them after taking informed consent. A pre-validated questionnaire regarding knowledge, awareness, and prescribing schedule of antihistamines was filled up. The data were then analyzed with suitable statistical tests.
Almost 73% of physicians prescribed second-generation antihistamines, while 27% prescribed the first-generation ones. Only 15% of them were aware about the ARIA and GA2LEN guidelines and their recommendations for prescribing second-generation antihistamines over the older first-generation antihistamines, while 85% had not heard about them previously. A minimum 7% of practitioners revealed that they updosed the same drug four times in the treatment of urticaria, while 93% did not do it.
Even though a sizeable percentage of family physicians prescribed second-generation antihistamines, most of them were not aware of their dosing guidelines.
抗组胺药是治疗过敏性疾病和瘙痒症常用的处方药之一。它们大致分为两代,第二代药物效果更佳且副作用更少。由于患者最初会因自身问题联系家庭医生,所以家庭医生经常使用抗组胺药。了解他们选择抗组胺药的方式会很有趣。
对100名家庭医生进行了研究。在获得知情同意后从他们那里收集原始数据。填写一份关于抗组胺药知识、认知度和处方时间表的预验证问卷。然后用合适的统计检验对数据进行分析。
几乎73%的医生开具第二代抗组胺药,而27%的医生开具第一代抗组胺药。只有15%的医生了解变应性鼻炎和变应性结膜炎及全球变应性和哮喘欧洲网络(ARIA and GA2LEN)指南以及其中关于优先开具第二代抗组胺药而非第一代抗组胺药的建议,而85%的医生之前从未听说过这些指南。至少7%的从业者表示,他们在治疗荨麻疹时将同一种药物加量了4次,而93%的从业者没有这样做。
尽管有相当比例的家庭医生开具第二代抗组胺药,但他们中的大多数并不了解其用药指南。