哌拉西林、替卡西林、美洛西林、替卡西林-克拉维酸、氨曲南、头孢他啶、阿洛西林、头孢哌酮和硫霉素对铜绿假单胞菌的体外活性。
In vitro activity of piperacillin, ticarcillin, mezlocillin, ticarcillin-clavulanic acid, aztreonam, ceftazidime, azlocillin, cefoperazone, and thienamycin against Pseudomonas aeruginosa.
作者信息
Greenberg R N, Bollinger M R, Alivisatos M R
出版信息
Clin Ther. 1986;8(6):655-7.
The in vitro susceptibility of 103 well-characterized strains of Pseudomonas aeruginosa to nine antimicrobial agents was assessed by means of the Kirby-Bauer disk diffusion assay and the microtiter minimal inhibitory concentration assay. The antimicrobials, from the most to the least active against P aeruginosa, were thienamycin greater than ceftazidime greater than piperacillin greater than azlocillin greater than cefoperazone greater than aztreonam greater than ticarcillin greater than ticarcillin-clavulanic acid greater than mezlocillin. The resistance patterns of the antimicrobial agents suggest that P aeruginosa resistant to a penicillin, cephalosporin, or aztreonam may be susceptible to thienamycin.
通过 Kirby-Bauer 纸片扩散法和微量滴定最小抑菌浓度法，评估了 103 株特征明确的铜绿假单胞菌菌株对九种抗菌药物的体外敏感性。对铜绿假单胞菌活性由高到低的抗菌药物依次为：亚胺培南＞头孢他啶＞哌拉西林＞阿洛西林＞头孢哌酮＞氨曲南＞替卡西林＞替卡西林-克拉维酸＞美洛西林。抗菌药物的耐药模式表明，对青霉素、头孢菌素或氨曲南耐药的铜绿假单胞菌可能对亚胺培南敏感。
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