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Clinical Trial Designs.

作者信息

Nair Brijesh

机构信息

Department of Dermatology, Military Hospital, Jaipur, Rajasthan, India.

出版信息

Indian Dermatol Online J. 2019 Mar-Apr;10(2):193-201. doi: 10.4103/idoj.IDOJ_475_18.

DOI:10.4103/idoj.IDOJ_475_18
PMID:30984604
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6434767/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/b8f3376f2db0/IDOJ-10-193-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/c3e620f57448/IDOJ-10-193-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/65f80ed61629/IDOJ-10-193-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/edef7bb0d173/IDOJ-10-193-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/2fe20fdfd814/IDOJ-10-193-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/c608c1a66079/IDOJ-10-193-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/fb5e613f93ce/IDOJ-10-193-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/965eea6f3a1a/IDOJ-10-193-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/b8f3376f2db0/IDOJ-10-193-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/c3e620f57448/IDOJ-10-193-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/65f80ed61629/IDOJ-10-193-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/edef7bb0d173/IDOJ-10-193-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/2fe20fdfd814/IDOJ-10-193-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/c608c1a66079/IDOJ-10-193-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/fb5e613f93ce/IDOJ-10-193-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/965eea6f3a1a/IDOJ-10-193-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6499/6434767/b8f3376f2db0/IDOJ-10-193-g008.jpg

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2
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Orphanet J Rare Dis. 2013 Mar 25;8:48. doi: 10.1186/1750-1172-8-48.
3
Adaptive clinical trials in oncology.肿瘤学中的适应性临床试验。
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4
Exploring the utility of N-acetylcysteine for loss of control eating: protocol of an open-label single-arm pilot study.探索N-乙酰半胱氨酸对失控性进食的效用：一项开放标签单臂试点研究的方案
Pilot Feasibility Stud. 2025 Feb 19;11(1):19. doi: 10.1186/s40814-025-01598-5.
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4
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