Doenhoff M, Musallam R, Bain J, McGregor A
Immunology. 1978 Nov;35(5):771-8.
CBA mice deprived of their T cells by means of thymectomy and anti-thymocyte serum and subsequently infected with Schistosoma mansoni were found to have substantially fewer parasite eggs in their faeces than similarly infected immunologically-intact control animals. The number of parasite eggs deposited in the tissues of T-cell deprived mice was by comparison only marginally lower than in control mice. Administration of serum obtained from normal mice with chronic S. mansoni infections partially restored the egg excretion rate in infected deprived mice, and also resulted in an increased number of eggs being deposited in the liver and intestine of these animals.
通过胸腺切除和抗胸腺细胞血清去除T细胞的CBA小鼠，随后感染曼氏血吸虫，结果发现其粪便中的寄生虫卵数量比同样感染的免疫健全对照动物少得多。相比之下，T细胞缺失小鼠组织中沉积的寄生虫卵数量仅略低于对照小鼠。给慢性感染曼氏血吸虫的正常小鼠的血清进行注射，部分恢复了感染缺失小鼠的排卵率，并且还导致这些动物肝脏和肠道中沉积的虫卵数量增加。
