Fernández-Guarino M, Aboín S, Barchino L, Arsuaga C, Lázaro Ochaita P
Servicio de Dermatología, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, España.
Servicio de Dermatología, Hospital Universitario Sanitas La Zarzuela, Universidad Francisco de Vitoria, Madrid, España.
Actas Dermosifiliogr (Engl Ed). 2019 Jul-Aug;110(6):490-493. doi: 10.1016/j.ad.2018.01.015. Epub 2019 Apr 13.
Generalized lichen planus can be difficult to treat. One alternative for patients who do not respond to common topical and systemic treatments, such as corticosteroids and oral antihistamines, is phototherapy. Narrowband UV-B phototherapy offers several advantages and is currently the main treatment modality. In this study, we present the results corresponding to 10 patients with generalized lichen planus treated with narrowband UV-B phototherapy. We performed a prospective study of adult patients with generalized lichen planus affecting more than 20% of their body surface area. A complete response was observed in 8 patients (80%) and the disease recurred in 2 of these (recurrence rate, 25%). These rates are similar to those reported in the literature reviewed. Narrowband UV-B phototherapy is a widely used alternative to systemic treatments in GLP, but there are very few reports of its results in the literature.
泛发性扁平苔藓可能难以治疗。对于那些对常见的局部和全身治疗（如皮质类固醇和口服抗组胺药）无反应的患者，光疗是一种选择。窄谱中波紫外线（NB-UVB）光疗具有多种优势，目前是主要的治疗方式。在本研究中，我们展示了10例接受窄谱中波紫外线光疗的泛发性扁平苔藓患者的治疗结果。我们对全身表面积受累超过20%的泛发性扁平苔藓成年患者进行了一项前瞻性研究。8例患者（80%）观察到完全缓解，其中2例复发（复发率为25%）。这些比率与文献综述中报道的相似。窄谱中波紫外线光疗是泛发性扁平苔藓全身治疗中广泛使用的替代方法，但文献中关于其治疗结果的报道非常少。
