紫外线B治疗皮肤扁平苔藓：我们对50例患者的经验。
Ultraviolet-B treatment for cutaneous lichen planus: our experience with 50 patients.
作者信息
Pavlotsky Felix, Nathansohn Nir, Kriger Grigory, Shpiro Dorit, Trau Henri
机构信息
Department of Dermatology, Phototherapy and Day Care Center, Chaim Sheba Medical Center, Tel Hashomer, Israel.
出版信息
Photodermatol Photoimmunol Photomed. 2008 Apr;24(2):83-6. doi: 10.1111/j.1600-0781.2008.00344.x.
BACKGROUND
Previous small reports suggested the role of ultraviolet (UV)-B in the management of cutaneous lichen planus.
OBJECTIVE
To summarize our experience with UVB in a relatively large study group looking specifically into predictive factors for complete response and the long-term relapse rates.
METHODS
A retrospective analysis of 50 patients with generalized cutaneous lichen planus, treated by broad or narrow band UVB.
RESULTS
Seven and 43 patients were treated by broad and narrow band UVB, respectively. Complete response was achieved in 70% and 85% of those were still in remission after a median of 34.7 months. The complete response rate and the need for higher cumulative exposure doses were not influenced by sex, age, skin type, presence of additional diseases, failure of previous treatment or disease duration.
LIMITATIONS
This is a retrospective non-randomized analysis of a usually self-limiting disease.
CONCLUSION
UVB is a safe and efficient treatment option for generalized cutaneous lichen planus.
背景
先前的小型报告提示紫外线B（UV-B）在皮肤扁平苔藓治疗中的作用。
目的
在一个相对较大的研究组中总结我们使用UVB的经验，特别研究完全缓解的预测因素和长期复发率。
方法
对50例泛发性皮肤扁平苔藓患者进行回顾性分析，这些患者接受了宽带或窄带UVB治疗。
结果
分别有7例和43例患者接受了宽带和窄带UVB治疗。70%和85%的患者获得了完全缓解，中位随访34.7个月后仍处于缓解状态。完全缓解率和累积暴露剂量需求不受性别、年龄、皮肤类型、是否存在其他疾病、既往治疗失败或病程的影响。
局限性
这是对一种通常为自限性疾病的回顾性非随机分析。
结论
UVB是泛发性皮肤扁平苔藓一种安全有效的治疗选择。
Zotero 插件