Laboratorio de Cromatografía, Facultad de Química, Universidad Autónoma de Yucatán, C. 43 No. 613 x C. 90, Col. Inalámbrica, C. P. 97069, Mérida, Yucatán, México.
Laboratorio de Espectrometría de Masas, Facultad de Química, Universidad Autónoma de Yucatán, C. 43 No. 613 x C. 90, Col. Inalámbrica, C. P. 97069, Mérida, Yucatán, México.
Bull Environ Contam Toxicol. 2019 Jun;102(6):836-842. doi: 10.1007/s00128-019-02609-x. Epub 2019 Apr 15.
The aim of the present work was to apply a validated methodology for the detection of organochlorine pesticides in Didelphis virginiana (Virginia opossum) serum samples collected in Yucatan, Mexico. Recent studies performed to investigate the presence of Organochlorines (OCLs) in water, human blood and milk, and animal tissues from Yucatan have shown that the OCLs concentrations are high and can be associated with potential human health risk. Since opossum is considered an important synanthropic species in Yucatan, 40 opossum serum samples were analyzed by gas chromatography with electron capture detector. The most common OCLs found in opossum sera were lindanes, chlordanes, drines, and endosulfan. Heptachlor, heptachlor epoxide, and lindanes were found at the highest concentrations, while dichlorodiphenyl trichloroethane and its metabolites were found at the lowest concentrations in the samples. The good linearity, precision, and accuracy obtained in the evaluated parameters in the extraction and chromatographic methods support its application for the monitoring of OCLs pesticides in populations of opossums and other wild species in Yucatan.
本研究旨在应用一种经过验证的方法来检测在墨西哥尤卡坦收集的袋獾血清样本中的有机氯农药。最近在尤卡坦进行的一些研究调查了水中、人类血液和牛奶以及动物组织中有机氯（OCLs）的存在情况，结果表明 OCLs 的浓度很高，可能对人类健康构成风险。由于袋獾被认为是尤卡坦的一种重要的伴生种，因此对 40 份袋獾血清样本进行了气相色谱 - 电子捕获检测分析。在袋獾血清中发现的最常见的 OCLs 是林丹、氯丹、狄氏剂和硫丹。在样本中发现含量最高的是七氯、七氯环氧化物和林丹，而滴滴涕及其代谢物的含量最低。在提取和色谱方法中评估的参数中获得的良好线性、精密度和准确度支持其在监测尤卡坦袋獾和其他野生动物种群中的 OCLs 农药方面的应用。
