Zhang Jian-Gang, Chen Ji-Jun, Geng Chang-An
State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences Kunming 650201,China Yunnan Key Laboratory of Natural Medicinal Chemistry Kunming 650201,China.
State Key Laboratory of Phytochemistry and Plant Resources in West China,Kunming Institute of Botany,Chinese Academy of Sciences Kunming 650201,China Yunnan Key Laboratory of Natural Medicinal Chemistry Kunming 650201,China University of Chinese Academy of Science Beijing 100049,China.
Zhongguo Zhong Yao Za Zhi. 2019 Feb;44(4):685-695. doi: 10.19540/j.cnki.cjcmm.20181121.006.
Uncaria genus( Rubiaceae) contains 34 species all over the world,of which 11 species and one variant are present in China. Five species,namely U. rhynchophylla,U. macrophylla,U. hirsuta,U. sinensis and U. sessilifructus,are documented in Chinese Pharmacopoeia as the raw materials of Uncariae Ramulus Cum Uncis. Indole alkaloids are the characteristic constituents of Uncaria plants,in addition to triterpenes,lignans and flavones. This paper reviews the progress of indole alkaloids and their distribution within the five Uncaria species documented in Chinese Pharmacopoeia for better understanding the active constituents of Uncariae Ramulus Cum Uncis.
钩藤属（茜草科）全球共有34个物种，其中中国有11个物种和1个变种。《中国药典》记载了5个物种，即钩藤、大叶钩藤、毛钩藤、华钩藤和无柄果钩藤，作为钩藤的原料。除三萜类、木脂素类和黄酮类外，吲哚生物碱是钩藤属植物的特征性成分。本文综述了《中国药典》记载的5种钩藤中吲哚生物碱及其分布的研究进展，以便更好地了解钩藤的活性成分。
