Department of Ophthalmology, Henry Ford Health System, Detroit, Michigan.
Retin Cases Brief Rep. 2021 Nov 1;15(6):734-737. doi: 10.1097/ICB.0000000000000874.
To describe multimodal imaging findings, including fundus autofluorescence, in a patient with a growing choroidal osteoma.
Case report.
A 13-year-old girl presented with an asymptomatic lesion in the superonasal macula of her left eye. Vision was correctable to 20/20 in both eyes, and the only significant finding on examination was the yellow flat lesion in the left macula. It measured 0.8-disk areas in size. Ocular coherence tomography showed a space occupying lesion in the choroid that had horizontal hyper-reflective lines consistent with cancellous bone. Re-examination in a year showed enlargement. Fundus autofluorescence showed no abnormalities in either eye. Ultrasonography showed a hyper-reflective lesion with associated shadowing that was consistent with a choroidal osteoma.
Normal fundus autofluorescence was seen in this young girl with a growing choroidal osteoma. Fundus autofluorescence is a proxy for the health of the retinal pigment epithelium. Normal retinal pigment epithelium is the only factor found to be predictive of future growth of a choroidal osteoma. This noninvasive test may prove useful as a guide to determine frequency of examinations especially in younger patients who might be prone to more rapid growth.
描述一位不断生长的脉络膜骨瘤患者的多模态影像学表现，包括眼底自发荧光。
病例报告。
一名 13 岁女孩左眼鼻上象限出现无症状病变。双眼矫正视力均为 20/20，左眼黄斑区有一黄色扁平病变，是唯一显著的检查发现。病变大小为 0.8 个盘区。眼部相干断层扫描显示脉络膜占位性病变，有水平高反射线，符合松质骨。一年后的复查显示病变增大。眼底自发荧光显示双眼均无异常。超声显示高反射病变伴相关阴影，符合脉络膜骨瘤。
这位不断生长的脉络膜骨瘤的年轻女孩眼底自发荧光正常。眼底自发荧光是视网膜色素上皮健康的指标。正常的视网膜色素上皮是唯一被发现可预测脉络膜骨瘤未来生长的因素。这种非侵入性检查可能有助于指导确定检查的频率，特别是对于可能更容易快速生长的年轻患者。
