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解析巨噬细胞和单核细胞的密码，对人类乳腺癌患者进行分类。

Deciphering Macrophage and Monocyte Code to Stratify Human Breast Cancer Patients.

机构信息

Department of Medicine, University of Verona, Policlinico GB Rossi, Piazzale L.A. Scuro 10, 37134 Verona, Italy.

出版信息

Cancer Cell. 2019 Apr 15;35(4):538-539. doi: 10.1016/j.ccell.2019.03.010.

DOI:10.1016/j.ccell.2019.03.010
PMID:30991022
Abstract

In this issue of Cancer Cell, Cassetta et al. present a detailed analysis of the transcriptional profile imprinted on monocytes and macrophages by human breast and endometrial cancers, proposing SIGLEC1 and CCL8 as novel biomarkers in tumor-associated macrophages for breast cancer patient stratification and prognosis.

摘要

在本期《癌细胞》中，Cassetta 等人对人类乳腺癌和子宫内膜癌在单核细胞和巨噬细胞上留下的转录特征进行了详细分析，提出 SIGLEC1 和 CCL8 可作为肿瘤相关巨噬细胞中的新型生物标志物，用于乳腺癌患者分层和预后判断。

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Deciphering Macrophage and Monocyte Code to Stratify Human Breast Cancer Patients.解析巨噬细胞和单核细胞的密码，对人类乳腺癌患者进行分类。
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