Section of Psychiatry, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy; Department of Neurosciences and Mental Health, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy.
Unit of Psychiatry, Department of Medicine (DAME), University of Udine, Udine, Italy.
J Affect Disord. 2019 Jun 1;252:245-252. doi: 10.1016/j.jad.2019.04.063. Epub 2019 Apr 8.
To date there are no validated tests in Italian to assess cognitive functions in Bipolar Disorder. Therefore, this study aimed to provide normative data for the Italian version of the Brief Assessment of Cognition in Affective Disorders (BAC-A), a battery targeting neuro- and affective-cognition in affective disorders.
Data were collected from 228 healthy participants (age range: 18-67; mean age: 34.68 ± 12.15 years) across eight recruiting sites. The influence of age, sex and education was measured and adjusted for using multivariate stepwise regression models. Normative values were established by means of the Equivalent Score approach.
Most of the BAC-A subtests showed patterns of association with age (inversely associated with overall cognitive performance), education (positively associated with Verbal Memory and Fluency, Digit Sequencing and Affective Processing subtests) and sex (females performed better than males in the Affective Interference Test but worse in the Emotion Inhibition Task, Digit Sequencing and Tower of London).
The sample size was not sufficiently large for developing stratified norms, using 10-years ranges. Moreover, the participants included in the study were, on average, highly educated.
The normative data of the BAC-A provided in this study can serve as a cognitive functioning reference for Italian-speaking participants within the age range of the study sample. This can increase the applicability of this test in both clinical and research settings. The reliability and validity of the Italian BAC-A need to be further investigated.
目前,意大利还没有经过验证的测试可以评估双相情感障碍患者的认知功能。因此,本研究旨在提供意大利版Brief Assessment of Cognition in Affective Disorders(BAC-A)的常模数据,该测试可评估情感障碍患者的神经认知和情感认知功能。
本研究共纳入了来自 8 个招募中心的 228 名健康参与者(年龄范围:18-67 岁;平均年龄:34.68±12.15 岁)。使用多元逐步回归模型测量和调整了年龄、性别和教育的影响。通过等分数法确定了常模值。
大多数 BAC-A 子测试与年龄(与整体认知表现呈负相关)、教育(与言语记忆、流畅性、数字序列和情感处理子测试呈正相关)和性别(女性在情感干扰测试中的表现优于男性,但在情绪抑制任务、数字序列和伦敦塔任务中的表现则更差)有关。
由于样本量不够大,无法按照 10 年为一个区间制定分层常模。此外,参与研究的参与者平均受教育程度较高。
本研究提供的 BAC-A 常模数据可作为研究样本年龄范围内讲意大利语的参与者的认知功能参考。这可以提高该测试在临床和研究环境中的适用性。意大利版 BAC-A 的可靠性和有效性还需要进一步研究。