Kumari K Ajitha, Jadhav Poonam D, Prasad Chaya, Smitha N V, Jojo Annie, Manjula V D
Department of Pathology, Believers Church Medical College, Thiruvalla, Kerala, India.
Department of Pathology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India.
J Cytol. 2019 Apr-Jun;36(2):101-105. doi: 10.4103/JOC.JOC_168_16.
Image-guided fine needle aspiration cytology (FNAC) is emerging as an important diagnostic tool in the evaluation of thyroid swellings.
This study aims to assess the efficacy of ultrasound (US)-guided FNAC combined with "The Bethesda system' of reporting as a primary screening test for all thyroid lesions.
A prospective cohort study was made and all the US-guided FNACs done were followed up to find out the histopathological diagnoses wherever surgery was done.
In all, 1050 patients who underwent US-guided FNAC were studied during a period of 1 year. Age, sex, cytological features, and histological diagnoses were analyzed. Statistical analyses of all the findings were done to derive conclusions.
Of the 1050 patients, only 10.5% underwent surgery. Higher than expected rate (as per the Bethesda system) of malignancy was noted with the so-called grey zone lesions. The test results revealed a high level of sensitivity, specificity, and diagnostic accuracy.
The study showed that The Bethesda System of Reporting Thyroid Cytology provides effective communication between clinician and pathologists thereby enabling clear management strategies. We also concluded that US-guided FNACs offer better results compared with palpation-guided FNACs.
影像引导下细针穿刺细胞学检查(FNAC)正在成为评估甲状腺肿物的一项重要诊断工具。
本研究旨在评估超声(US)引导下FNAC联合“贝塞斯达系统”报告作为所有甲状腺病变的初步筛查试验的有效性。
进行了一项前瞻性队列研究,对所有接受US引导下FNAC的患者进行随访,以查明无论何处进行手术的组织病理学诊断。
在1年的时间里,共研究了1050例接受US引导下FNAC的患者。分析了年龄、性别、细胞学特征和组织学诊断。对所有结果进行统计分析以得出结论。
1050例患者中,仅10.5%接受了手术。在所谓的灰色区域病变中,观察到高于预期(根据贝塞斯达系统)的恶性率。检测结果显示出高水平的敏感性、特异性和诊断准确性。
该研究表明,甲状腺细胞病理学报告的贝塞斯达系统在临床医生和病理学家之间提供了有效的沟通,从而能够制定明确的管理策略。我们还得出结论,与触诊引导下的FNAC相比,US引导下的FNAC效果更好。