Peng Yuan, Yang Xiao, Chen Wei, Yu Xue-Qing
Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510080, China.
Key Laboratory of Nephrology, National Health Commission and Guangdong Province, Guangzhou, Guangdong 510080, China.
Chronic Dis Transl Med. 2018 Dec 21;5(1):37-43. doi: 10.1016/j.cdtm.2018.10.001. eCollection 2019 Mar.
Despite the widespread use of chronic dialysis for end-stage renal disease (ESRD), there is no consensus on the optimal timing of initiating renal replacement therapy. Over the past decade, a worldwide trend toward increasing glomerular filtration rate at the initiation of dialysis has been noted. However, available data indicate that early dialysis has no survival benefit or is harmful. Peritoneal dialysis (PD) is one alternative for ESRD and has potential survival factors different from those of hemodialysis. The association between the timing of PD initiation and survival is unclear. This review examines the effect of the timing of dialysis on clinical outcomes in PD patients.
尽管慢性透析在终末期肾病（ESRD）中广泛应用，但对于开始肾脏替代治疗的最佳时机尚无共识。在过去十年中，已注意到全球范围内透析开始时肾小球滤过率增加的趋势。然而，现有数据表明早期透析没有生存益处或有害。腹膜透析（PD）是ESRD的一种替代方法，具有与血液透析不同的潜在生存因素。PD开始时机与生存之间的关联尚不清楚。本综述探讨透析时机对PD患者临床结局的影响。
