Komarov R N, Karavaĭkin P A, Kuznetsov A A, Shcherbenev V M, Bredikhin R A, Gnevashev A S, Iudin A N, Tsekhanovich V N, Andreev D B
Clinic of Aortic and Cardiovascular Surgery, Chair of Hospital Surgery of Therapeutic Department, First Moscow State Medical University named after I.M. Sechenov under the RF Ministry of Public Health, Moscow, Russia.
Central Military Clinical Hospital named after A.A. Vishnevsky of the RF Ministry of Defence, Moscow, Russia.
Angiol Sosud Khir. 2019;25(1):131-142. doi: 10.33529/angio2019118.
The problem of haemostasis in cardiovascular surgery is of current concern. Recent trends are towards increased use of topical haemostatic agents. Tachocomb has been used for more than 30 years in abdominal surgery and oncology. The purpose of the present publication is to analyse the literature data and formulate the indications for the use of Tachocomb in cardiovascular surgery. Multicenter randomized and local studies have demonstrated efficacy of Tachocomb in treatment of surgical haemorrhage in operations on the heart, thoracic aorta, carotid arteries and lower-limb arteries, resulting in significantly decreased time to achieve haemostasis, decreased volume of blood loss and haemotrasfusion, as well as reduced frequency of complications. Also shown was economic efficacy, including a shortened length of patients' hospital stay. This is followed by describing a wide spectrum of examples of alternative use of Tachocomb, including its use for seamless closure of defects of cardiac chamber walls, aero- and lymphostasis, prevention of formation of commissures. Convincing experimental and clinical results make it possible to formulate a series of indications for the use of Tachocomb in cardiovascular surgery.
心血管手术中的止血问题是当前备受关注的。近期趋势是局部止血剂的使用有所增加。速即纱已在腹部手术和肿瘤学领域使用了30多年。本出版物的目的是分析文献数据并制定速即纱在心血管手术中的使用指征。多中心随机研究和局部研究已证明速即纱在治疗心脏、胸主动脉、颈动脉和下肢动脉手术中的手术出血方面具有疗效，可显著缩短止血时间、减少失血量和输血量，并降低并发症发生率。还显示出其经济效益，包括缩短患者住院时间。接下来描述了速即纱广泛的替代用途示例，包括用于无缝闭合心腔壁缺损、气性和淋巴性止血、预防连合形成。令人信服的实验和临床结果使得能够制定速即纱在心血管手术中的一系列使用指征。
