Sharmanov T Sh, Nikov P S, Aldabergenova K U, Meerbekova B T
Vopr Pitan. 1986 Sep-Oct(5):56-60.
Deficiency of the essential nutrients lysine, methionine, threonine and vitamins A, E, C significantly increases the mutagenic environment of somatic cells in growing Wag rats. Aflatoxin B1 produces a pronounced mutagenic effect on the cellular genetic apparatus; this effect is substantially modified due to the nutrition character: it is either intensified or inhibited. The results obtained suggest that the nutritional factors can de used for prevention and elimination of aflatoxin B1-induced mutations.
必需营养素赖氨酸、蛋氨酸、苏氨酸以及维生素A、E、C的缺乏会显著增加生长中的Wag大鼠体细胞的诱变环境。黄曲霉毒素B1对细胞遗传机制产生明显的诱变作用；这种作用会因营养特性而发生实质性改变：要么增强，要么受到抑制。所得结果表明，营养因素可用于预防和消除黄曲霉毒素B1诱导的突变。
