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本文引用的文献

1
Deactivation of Implantable Cardioverter-Defibrillators in Heart Failure: A Systematic Review.心力衰竭患者植入式心脏复律除颤器的停用:一项系统评价
J Hosp Palliat Nurs. 2018 Feb;20(1):63-71. doi: 10.1097/NJH.0000000000000399.
2
The incidence and impact of implantable cardioverter defibrillator shocks in the last phase of life: An integrated review.植入式心脏复律除颤器电击在生命末期的发生率及影响:一项综合综述。
Eur J Cardiovasc Nurs. 2018 Aug;17(6):477-485. doi: 10.1177/1474515118777421. Epub 2018 May 18.
3
Patient and Professional Factors That Impact the Perceived Likelihood and Confidence of Healthcare Professionals to Discuss Implantable Cardioverter Defibrillator Deactivation in Advanced Heart Failure: Results From an International Factorial Survey.影响医护专业人员在晚期心力衰竭中讨论植入式心律转复除颤器去激活的可能性和信心的患者与专业因素:来自一项国际析因调查的结果。
J Cardiovasc Nurs. 2018 Nov/Dec;33(6):527-535. doi: 10.1097/JCN.0000000000000500.
4
The State of the Science on Integrating Palliative Care in Heart Failure.心力衰竭中整合姑息治疗的科学现状
J Palliat Med. 2017 Jun;20(6):592-603. doi: 10.1089/jpm.2017.0178. Epub 2017 May 12.
5
The ecisions, nterventions, and oals in Implatable Cardioverter-Defbrillator herap (DIGNITY) Pilot Study.可植入心脏除颤器治疗(DIGNITY)先导研究中的决策、干预和目标。
J Am Heart Assoc. 2017 Sep 22;6(9):e006881. doi: 10.1161/JAHA.117.006881.
6
Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care.预先医疗照护计划的定义和建议:欧洲缓和医疗协会支持的国际共识。
Lancet Oncol. 2017 Sep;18(9):e543-e551. doi: 10.1016/S1470-2045(17)30582-X.
7
End-of-Life Decisions in the Netherlands over 25 Years.25年来荷兰的临终决策
N Engl J Med. 2017 Aug 3;377(5):492-494. doi: 10.1056/NEJMc1705630.
8
Cardiovascular implanted electronic devices in people towards the end of life, during cardiopulmonary resuscitation and after death: guidance from the Resuscitation Council (UK), British Cardiovascular Society and National Council for Palliative Care.心血管植入式电子设备在临终患者、心肺复苏期间及死后的应用:英国复苏委员会、英国心血管学会和国家姑息治疗委员会的指南
Heart. 2016 Jun;102 Suppl 7:A1-A17. doi: 10.1136/heartjnl-2016-309721.
9
Palliative care in patients with heart failure.心力衰竭患者的姑息治疗。
BMJ. 2016 Apr 14;353:i1010. doi: 10.1136/bmj.i1010.
10
Palliative Care Consultation and Associated End-of-Life Care After Pacemaker or Implantable Cardioverter-Defibrillator Deactivation.起搏器或植入式心律转复除颤器停用后的姑息治疗咨询及相关临终关怀
Am J Hosp Palliat Care. 2016 Dec;33(10):966-971. doi: 10.1177/1049909115595017. Epub 2015 Jul 12.

生命末期植入式心脏转复除颤器管理的时间趋势:病历回顾性研究。

Trends in time in the management of the implantable cardioverter defibrillator in the last phase of life: a retrospective study of medical records.

机构信息

1 Department of Public Health, Erasmus University Medical Center Rotterdam, The Netherlands.

2 Department of Cardiology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.

出版信息

Eur J Cardiovasc Nurs. 2019 Aug;18(6):449-457. doi: 10.1177/1474515119844660. Epub 2019 Apr 17.

DOI:10.1177/1474515119844660
PMID:30995145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6661715/
Abstract

BACKGROUND

The implantable cardioverter defibrillator (ICD) might give unwanted shocks in the last month of life. Guidelines recommend deactivation of the ICD prior to death.

AIMS

The aims of this study were to examine trends in time (2007-2016) in how and when decisions are made about ICD deactivation, and to examine patient- and disease-related factors which may have influenced these decisions. In addition, care and ICD shock frequency in the last month of life of ICD patients are described.

METHODS

Medical records of a sample of deceased patients who had their ICD implanted in 1999-2015 in a Dutch university ( = 308) or general ( = 72) hospital were examined.

RESULTS

Median age at death was 71 years, and 88% were male. ICD deactivation discussions increased from 6% for patients who had died between 2007 and 2009 to 35% for patients who had died between 2013 and 2016. ICD deactivation rates increased in these periods from 16% to 42%. Presence of do-not-resuscitate (DNR) orders increased from 9% to 46%. Palliative care consultations increased from 0% to 9%. When the ICD remained active, shocks were reported for 7% of patients in the last month of life. Predictors of ICD deactivation were the occurrence of ICD deactivation discussions after implantation (OR 69.30, CI 26.45-181.59), DNR order (OR 6.83, CI 4.19-11.12), do-not-intubate order (OR 6.41, CI 3.75-10.96), and palliative care consultations (OR 8.67, CI 2.76-27.21).

CONCLUSION

ICD deactivation discussions and deactivation rates have increased since 2007. Nevertheless, ICDs remain active in the majority of patients at the end of life, some of whom experience shocks.

摘要

背景

植入式心脏复律除颤器(ICD)可能在生命的最后一个月发出不必要的电击。指南建议在死亡前停用 ICD。

目的

本研究旨在探讨 2007 年至 2016 年间,关于 ICD 停用决策的时间和方式的趋势,并探讨可能影响这些决策的患者和疾病相关因素。此外,还描述了 ICD 患者生命最后一个月的护理和 ICD 电击频率。

方法

检查了 1999 年至 2015 年期间在荷兰一所大学(=308)或普通(=72)医院植入 ICD 的一组已故患者的病历。

结果

死亡时的中位年龄为 71 岁,88%为男性。2007 年至 2009 年期间死亡的患者中,ICD 停用讨论比例为 6%,而 2013 年至 2016 年期间死亡的患者中,ICD 停用讨论比例为 35%。在此期间,ICD 停用率从 16%增加到 42%。不复苏(DNR)医嘱的比例从 9%增加到 46%。姑息治疗咨询从 0%增加到 9%。当 ICD 仍然活跃时,7%的患者在生命的最后一个月报告有电击。ICD 停用的预测因素包括植入后 ICD 停用讨论的发生(OR 69.30,95%CI 26.45-181.59)、DNR 医嘱(OR 6.83,95%CI 4.19-11.12)、不插管医嘱(OR 6.41,95%CI 3.75-10.96)和姑息治疗咨询(OR 8.67,95%CI 2.76-27.21)。

结论

自 2007 年以来,ICD 停用讨论和停用率有所增加。然而,在生命的最后阶段,大多数患者的 ICD 仍然活跃,其中一些人经历了电击。