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一名患有产后因子VIII抑制剂的患者的正常妊娠。

Normal pregnancy in a patient with a postpartum factor VIII inhibitor.

作者信息

Vicente V, Alberca I, Gonzalez R, Alegre A

出版信息

Am J Hematol. 1987 Jan;24(1):107-9. doi: 10.1002/ajh.2830240114.

DOI:10.1002/ajh.2830240114
PMID:3099565
Abstract

A patient who had developed a VIII:C IgG-Kappa antibody after her first delivery became pregnant for a second time. At that time the titer of the inhibitor had increased fourfold, remaining at high levels throughout the rest of the pregnancy. The neonate exhibited an inhibitor with characteristics identical to that of the mother which could not be detected 3 months after birth. No hemorrhagic complications in either of the subjects were observed.

摘要

一名患者在首次分娩后产生了VIII:C IgG-Kappa抗体,第二次怀孕。当时,抑制剂的滴度增加了四倍,在整个孕期的其余时间都维持在高水平。新生儿表现出与母亲相同特征的抑制剂,出生3个月后无法检测到。两名受试者均未观察到出血并发症。

相似文献

1
Normal pregnancy in a patient with a postpartum factor VIII inhibitor.一名患有产后因子VIII抑制剂的患者的正常妊娠。
Am J Hematol. 1987 Jan;24(1):107-9. doi: 10.1002/ajh.2830240114.
2
Normal pregnancy in a patient with a prior postpartum factor VIII inhibitor: with observations on pathogenesis and prognosis.既往有产后因子VIII抑制剂的患者的正常妊娠:关于发病机制和预后的观察
Blood. 1981 Sep;58(3):619-24.
3
Case of acquired hemophilia with factor VIII inhibitor in a mother and newborn.
J Obstet Gynaecol Res. 2011 Aug;37(8):1102-5. doi: 10.1111/j.1447-0756.2010.01462.x. Epub 2011 Mar 31.
4
[Non-hemophilic patient with inhibitor against factor VIII produced after the second delivery].[非血友病患者在第二次分娩后产生针对凝血因子VIII的抑制物]
Rinsho Byori. 1999 Sep;47(9):891-5.
5
Coagulopathy associated with factor VIII inhibitor. A literature review.与凝血因子VIII抑制剂相关的凝血病。文献综述。
J Reprod Med. 1984 Jan;29(1):53-8.
6
[Postpartum hemophilia A with factor VIII inhibitor].
Dtsch Med Wochenschr. 1985 May 17;110(20):799-802. doi: 10.1055/s-2008-1068907.
7
[Postpartum hemorrhage syndrome caused by factor VIII inhibitor in the blood].血液中 VIII 因子抑制物所致产后出血综合征
Bilt Hematol Transfuz. 1975;3(3):35-40.
8
[Postpartum factor VIII inhibitor associated with primary biliary cirrhosis: a case report].[产后与原发性胆汁性肝硬化相关的因子 VIII 抑制剂:一例报告]
Nihon Naika Gakkai Zasshi. 1986 Jan;75(1):40-5. doi: 10.2169/naika.75.40.
9
Postpartum factor VIII inhibitors. Report of two cases with special reference to the efficacy of various treatments.
Wien Klin Wochenschr. 1993;105(12):355-8.
10
Pregnancy and antibody to factor VIII.妊娠与抗凝血因子VIII抗体
J Clin Pathol. 1977 Oct;30(10):928-32. doi: 10.1136/jcp.30.10.928.

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Investigation and management of haemorrhagic disorders in pregnancy. Haemostasis and Thrombosis Task Force.妊娠期出血性疾病的调查与管理。止血与血栓形成特别工作组。
J Clin Pathol. 1994 Feb;47(2):100-8. doi: 10.1136/jcp.47.2.100.