Voke J, Letsky E
J Clin Pathol. 1977 Oct;30(10):928-32. doi: 10.1136/jcp.30.10.928.
A patient who had developed a factor VIII antibody three weeks after the birth of her first baby became pregnant for the second time 10 weeks later. The pregnancy was normal apart from extensive spontaneous bruising during the first two months. This bleeding tendency disappeared in the third month of gestation and the antibody became undetectable during the eighth month. It has not reappeared seven months later. An unexplained long bleeding time and low platelet count were noted during the last trimester. The literature on postpartum coagulation inhibitors is reviewed.
一名患者在其第一个孩子出生三周后产生了VIII因子抗体，10周后再次怀孕。除了在头两个月出现广泛的自发性瘀伤外，此次妊娠过程正常。这种出血倾向在妊娠第三个月消失，抗体在第八个月时检测不到。七个月后抗体未再出现。在妊娠晚期发现了原因不明的出血时间延长和血小板计数低的情况。本文对产后凝血抑制剂的文献进行了综述。
