美国阿拉斯加北坡一只自由放养的隐睾成年斑海豹（Phoca largha）发生转移性睾丸支持细胞瘤。

Metastatic testicular Sertoli cell tumor in a free-ranging cryptorchid adult spotted seal Phoca largha in North Slope, Alaska, USA.

作者信息

Rotstein David S, Stimmelmayr Raphaela, Adams Billy, Pederson Mike

机构信息

Marine Mammal Pathology Services, Olney, MD 20832, USA.

出版信息

Dis Aquat Organ. 2019 Feb 7;133(1):1-5. doi: 10.3354/dao03338.

DOI:10.3354/dao03338

PMID:30997879

Abstract

This case describes a metastatic Sertoli cell tumor (SCT) with lymphatic spread to the abdominal and thoracic lymph nodes, pancreas, and adrenal gland in an adult spotted seal Phoca largha. The neoplasm was composed of tubules lined by palisading neoplastic cells separated by a variably dense fibrous stroma. This pinniped was 1 of 2 cryptorchid seals and the sole case of genital neoplasia among 70 ice seals necropsied by the North Slope Borough from 2012 to 2017. Overall, SCTs are rarely reported in marine mammals.

摘要

本病例描述了一只成年斑海豹（Phoca largha）发生的转移性支持细胞瘤（SCT），肿瘤经淋巴管扩散至腹部和胸部淋巴结、胰腺及肾上腺。肿瘤由呈栅栏状排列的肿瘤细胞衬覆的小管组成，其间为密度不一的纤维性间质。这只鳍足类动物是2只隐睾海豹之一，也是2012年至2017年期间北坡自治市镇剖检的70只海豹中唯一发生生殖系统肿瘤的病例。总体而言，海洋哺乳动物中很少有支持细胞瘤的报道。