Labye L, Wenders F, Nisolle M, Henry L
Université de Liège, Belgique.
Service de Gynécologie-Obstétrique, CHR Citadelle, Liège, Belgique.
Rev Med Liege. 2019 Apr;74(4):192-196.
This retrospective study compares the impact of TSH level on the result of intrauterine insemination (IUI) with donor sperm in fertile women. There is no difference in women characteristics and their fertility. Despite the fact that the thyroid hormones influence fertility, this study shows that TSH before IUI doesn't influence pregnancy and live birth rates. However, thyroid hormones are important for the foetal brain development and pregnancy. Therefore, it is important to evaluate the thyroid function and prescribe a treatment if needed, (if TSH superior to 2.5 mUI/l) as the pregnancy is a stressful factor for thyroid and an infraclinical hypothyroidism can evolve into a clinical hypothyroidism in pregnant women.
这项回顾性研究比较了促甲状腺激素（TSH）水平对有生育能力的女性接受供体精子宫腔内人工授精（IUI）结果的影响。女性的特征及其生育能力并无差异。尽管甲状腺激素会影响生育能力，但本研究表明，IUI前的TSH水平不会影响妊娠率和活产率。然而，甲状腺激素对胎儿大脑发育和妊娠很重要。因此，评估甲状腺功能并在必要时（如果TSH高于2.5 mUI/l）进行治疗很重要，因为妊娠对甲状腺来说是一个应激因素，亚临床甲状腺功能减退在孕妇中可能会发展为临床甲状腺功能减退。
