Respiratory Department, Musgrove Park Hospital, Taunton.
Academic Respiratory Unit, University of Bristol, Bristol, UK.
Curr Opin Pulm Med. 2019 Jul;25(4):380-383. doi: 10.1097/MCP.0000000000000587.
Malignant pleural effusion is a common cause of breathlessness and signifies advanced disease. Common options for definitive pleural intervention include insertion of an indwelling pleural catheter (IPC) or talc pleurodesis.
Administration of graded talc through an IPC offers an increased chance of pleurodesis compared with IPC drainage alone and is not associated with a significant risk of adverse events.
In patients where an ambulatory treatment pathway is preferred, the increased chance of pleurodesis with talc administration via IPC can result in a faster time to device removal and may be associated with better quality of life and symptom scores.
恶性胸腔积液是呼吸困难的常见原因，表明疾病已进入晚期。根治性胸膜介入的常见选择包括留置胸膜导管（IPC）或滑石粉胸膜固定术。
与单独引流 IPC 相比，通过 IPC 给予分级滑石粉可增加胸膜固定术的机会，且与不良事件的显著风险无关。
在患者更倾向于门诊治疗路径的情况下，IPC 给予滑石粉增加胸膜固定术的机会可加快设备移除的时间，并且可能与更好的生活质量和症状评分相关。
