Department of Internal Medicine, Sanford School of Medicine, University of South Dakota, Vermillion.
Department of Nephrology and Transplantation, Sanford Medical Center, Sioux Falls, South Dakota.
Am J Med. 2019 Oct;132(10):e727-e732. doi: 10.1016/j.amjmed.2019.03.036. Epub 2019 Apr 15.
Patients residing in agricultural communities have a high risk of developing chronic kidney disease. In the Great Plains, geo-environmental risk factors (eg, variable climate, temperature, air quality, water quality, and drought) combine with agro-environmental risk factors (eg, exposure to fertilizers, soil conditioners, herbicides, fungicides, and pesticides) to increase risk for toxic nephropathy. However, research defining the specific influence of agricultural chemicals on the progression of kidney disease in rural communities has been somewhat limited. By linking retrospective clinical data within electronic medical records to environmental data from sources like US Environmental Protection Agency, analytical models are beginning to provide insight into the impact of agricultural practices on the rate of progression for kidney disease in rural communities.
居住在农业社区的患者患有慢性肾脏病的风险很高。在大平原地区,地质环境风险因素(如气候变化、温度、空气质量、水质和干旱等)与农业环境风险因素(如接触肥料、土壤调节剂、除草剂、杀菌剂和杀虫剂)相结合,增加了毒理性肾病的风险。然而,关于农业化学品对农村社区肾脏病进展具体影响的研究有些有限。通过将电子病历中的回顾性临床数据与美国环境保护署等来源的环境数据相联系,分析模型开始提供有关农业实践对农村社区肾脏病进展速度影响的见解。