脉络膜新生血管并发慢性中心性浆液性脉络膜视网膜病变：多模态成像的发现率
Choroidal Neovascularisation Complicating Chronic Central Serous Chorioretinopathy: The Discovery Rate on Multimodal Imaging.
作者信息
Romdhane Khaled, Mantel Irmela
机构信息
Department of Ophthalmology, University of Lausanne, Jules Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland.
出版信息
Klin Monbl Augenheilkd. 2019 Apr;236(4):536-541. doi: 10.1055/a-0834-6118. Epub 2019 Apr 18.
PURPOSE
To identify the image modality allowing identification of choroidal neovascularisation (CNV) complicating chronic central serous chorioretinopathy (CSCR), including fluorescein angiography (FA), indocyanine green angiography (ICGA), and optical coherence tomography angiography (OCT-A).
METHODS
Patients diagnosed with chronic CSCR and secondary CNV were included in the study. The image modalities FA, ICGA, and OCT-A were reviewed for specific CNV signs permitting diagnosis. Patients with missing image modalities, poor image quality, previous laser treatment, or other confounding pathologies were excluded.
RESULTS
CNV was identified on OCT-A in 32 of 33 eyes (97%), whereas ICGA revealed an abnormal vascular network in 23 eyes (70%), significantly less frequently than with OCT-A (p = 0.003). FA allowed CNV identification in 10 eyes (30%), significantly less frequently than with OCT-A (p < 0.001). Type 1 CNV was detected by OCT-A in 29 of 30 eyes (97%), by ICGA in 20 eyes (67%; p = 0.0027), and by FA in 8 eyes (27%; p < 0.001).
CONCLUSIONS
OCTA is a useful diagnostic tool to detect occult CNV complicating chronic CSCR. This image modality might be important for adequate patient care.
目的
确定能够识别并发慢性中心性浆液性脉络膜视网膜病变（CSCR）的脉络膜新生血管（CNV）的影像模式，包括荧光素血管造影（FA）、吲哚菁绿血管造影（ICGA）和光学相干断层扫描血管造影（OCT-A）。
方法
将诊断为慢性CSCR和继发性CNV的患者纳入研究。对FA、ICGA和OCT-A等影像模式进行评估，以寻找有助于诊断的特定CNV体征。排除影像模式缺失、图像质量差、既往接受过激光治疗或存在其他混淆性病变的患者。
结果
33只眼中有32只（97%）通过OCT-A识别出CNV，而ICGA显示23只眼（70%）存在异常血管网络，其检出频率显著低于OCT-A（p = 0.003）。FA在10只眼（30%）中识别出CNV，其检出频率显著低于OCT-A（p < 0.001）。30只眼中有29只（97%）通过OCT-A检测到1型CNV，2%）通过ICGA检测到（67%；p = 0.0027），8只眼（27%）通过FA检测到（p < 0.001）。
结论
OCTA是检测并发慢性CSCR的隐匿性CNV的有用诊断工具。这种影像模式对患者的充分治疗可能很重要。
Zotero 插件