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右侧瓣膜性心内膜炎导致反复肺脓肿的延迟诊断:一例报告

Delayed diagnosis of right-sided valve endocarditis causing recurrent pulmonary abscesses: a case report.

作者信息

Bamford Paul, Soni Rajeev, Bassin Levi, Kull Anthony

机构信息

Gosford Hospital, Holden Street, Gosford, NSW, 2250, Australia.

University of Newcastle, Newcastle, NSW, Australia.

出版信息

J Med Case Rep. 2019 Apr 19;13(1):97. doi: 10.1186/s13256-019-2034-7.

Abstract

BACKGROUND

Pulmonary valve infective endocarditis is a rare diagnosis that is usually associated with immunocompromised states or structurally abnormal hearts. It is unusual for it to occur in structurally normal hearts or to cause recurrent symptoms after targeted antibiotics. Although guidelines suggest follow-up with repeat echocardiography and inflammatory marker surveillance, this case demonstrates that these are not always useful investigations, and instead imaging of the chest may be more appropriate.

CASE PRESENTATION

We describe a case of a 74-year-old man who presented with respiratory symptoms and was originally misdiagnosed with pneumonia but later found to have a large pulmonary valve vegetation caused by Streptococcus mitis. Despite initially responding to antibiotic therapy, the vegetation continued to cause pulmonary emboli and cavitating lung abscesses months later, necessitating pulmonary valve replacement.

CONCLUSIONS

This case demonstrates that pulmonary valve endocarditis can present atypically with recurrent respiratory symptoms, and in such cases, echocardiography should be considered to investigate for right-sided infective endocarditis. In addition, despite correct treatment, with normalization of inflammatory markers and improvement in vegetation size, infective endocarditis can continue to cause systemic symptoms. Finally, clinicians should consider chest computed tomography routinely as part of right-sided infective endocarditis follow-up.

摘要

背景

肺动脉瓣感染性心内膜炎是一种罕见的诊断,通常与免疫功能低下状态或结构异常的心脏有关。它在结构正常的心脏中发生或在使用针对性抗生素后引起复发症状的情况并不常见。尽管指南建议通过重复超声心动图和炎症标志物监测进行随访,但本病例表明这些检查并非总是有用,相反,胸部成像可能更合适。

病例报告

我们描述了一名74岁男性的病例,他因呼吸道症状就诊,最初被误诊为肺炎,但后来发现患有由缓症链球菌引起的巨大肺动脉瓣赘生物。尽管最初对抗生素治疗有反应,但数月后赘生物继续导致肺栓塞和肺脓肿空洞形成,需要进行肺动脉瓣置换。

结论

本病例表明,肺动脉瓣心内膜炎可表现为非典型的复发性呼吸道症状,在这种情况下,应考虑进行超声心动图检查以排查右侧感染性心内膜炎。此外,尽管治疗正确,炎症标志物恢复正常且赘生物大小有所改善,但感染性心内膜炎仍可继续引起全身症状。最后,临床医生应常规将胸部计算机断层扫描作为右侧感染性心内膜炎随访的一部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00c4/6474058/491ba896f17e/13256_2019_2034_Fig1_HTML.jpg

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