Li Dan, Zhu Zhicheng, Zheng Xiaomei, Wang Weitie, Xu Rihao, Liu Kexiang
Department of Cardiovascular Surgery, The Second Hospital of Jilin University, 218 Ziqiang Street, Nanguan District, Changchun, Jilin, 130041, People's Republic of China.
Department of Cardiovascular Surgery, The First Hospital of Tianjin, No. 186 Nankou Road, Tianjin, 300232, People's Republic of China.
J Cardiothorac Surg. 2017 Mar 23;12(1):16. doi: 10.1186/s13019-017-0579-3.
Pulmonary valve infective endocarditis is a rare finding for endocarditis. Infective endocarditis caused by Gemella morbillorum remains a scanty occurrence.
This is a case reported of a 28-year-old Chinese male with endocarditis caused by pulmonary valve infection of Gemella morbillorum associated with congenital ventricular septal defect, atrial septal defect and double-chambered right ventricle. The patient presented with fever, shortness of breath, progressively worsening exertional fatigue, dyspnea and weight loss for 3 months. The diagnosis was made with transthoracic echocardiogram, blood cultures, and post-operative pathology. The patient developed congestive heart failure and was managed with aggressive antibiotic therapy followed by surgery. He underwent replacement of the pulmonary valve with an aortic bioprosthetic valve, repair of ventricular septal defect and atrial septal defect, reconstruction of the right ventricular outlflow tract, and excision of vegetations. His postoperative recovery was uneventful. No bacteria were isolated from the excised tissues. He was asymptomatic without recurrence at 3-month follow-up.
The rare pathogen such as Gemella morbillorum can be the cause of infective endocarditis and timely surgical repair is necessary if the infection is refractory or there is progression of congestive heart failure under antibiotic cover.
肺动脉瓣感染性心内膜炎是感染性心内膜炎中罕见的表现。由麻疹孪生球菌引起的感染性心内膜炎仍然很少见。
本文报道一例28岁中国男性,因麻疹孪生球菌肺动脉瓣感染导致感染性心内膜炎,合并先天性室间隔缺损、房间隔缺损和右心室双腔心。患者出现发热、气短、进行性加重的劳力性疲劳、呼吸困难和体重减轻3个月。通过经胸超声心动图、血培养和术后病理检查做出诊断。患者出现充血性心力衰竭,先接受积极的抗生素治疗,随后接受手术治疗。他接受了主动脉生物瓣置换肺动脉瓣、室间隔缺损和房间隔缺损修补、右心室流出道重建以及赘生物切除。术后恢复顺利。切除组织未分离出细菌。3个月随访时无症状且无复发。
像麻疹孪生球菌这样的罕见病原体可导致感染性心内膜炎,如果感染难治或在抗生素治疗下出现充血性心力衰竭进展,则需要及时进行手术修复。