Bakhet Wahba Z, Wahba Hassan A, El Fiky Lobna M, Debis Hossam
Department of Anesthesia, Ain Shams University, Cairo, Egypt.
Department of Otolaryngology, Ain Shams University, Cairo, Egypt.
Indian J Anaesth. 2019 Apr;63(4):304-309. doi: 10.4103/ija.IJA_754_18.
The anaesthesia technique for paediatric cochlear implantation should be modified to achieve an optimised surgical field and allow neuromonitoring. Total intravenous anaesthesia (TIVA) provides good surgical condition without affecting intraoperative electrical stapaedial reflex threshold (ESRT). Though magnesium sulphate (MgSO) is a cheap, readily available drug for controlled hypotension, it can decrease the amplitude of motor-evoked potentials. This study aimed to evaluate the effect of MgSO infusion on quality of surgical field, intraoperative ESRT, and anaesthetic requirements in paediatric cochlear implant surgery performed under TIVA.
In this randomised controlled trial, 66 children (1-6 years) undergoing cochlear implant under TIVA were randomly assigned to control group or MgSO group. The primary outcome was quality of surgical field, and the secondary outcomes were mean arterial blood pressure (MAP), heart rate (HR), ESRT, and the intraoperative anaesthetic requirements. The incidence of adverse events was recorded as well.
The quality of surgical field was better in group M than group C, < 0.02. The number of children who achieved optimum surgical conditions (scores ≤2) was significantly better in the group M ( = 23/33, 70%) compared with group C ( = 13/33, 39%), < 0.001. MAP, HR, and anaesthetic requirements were significantly lower in group M, < 0.05. There were no differences between both groups regarding ESRT response.
Magnesium sulphate IV infusion optimised surgical field and decreased anaesthetic requirements without attenuating the ESRT in paediatric cochlear implant surgery performed under TIVA.
小儿人工耳蜗植入术的麻醉技术应进行调整,以获得优化的手术视野并便于神经监测。全静脉麻醉(TIVA)可提供良好的手术条件,且不影响术中镫骨肌电反射阈值(ESRT)。硫酸镁(MgSO)虽是一种用于控制性低血压的廉价且易于获取的药物,但它会降低运动诱发电位的幅度。本研究旨在评估在TIVA下进行的小儿人工耳蜗植入手术中,输注MgSO对手术视野质量、术中ESRT及麻醉需求的影响。
在这项随机对照试验中,66例接受TIVA下人工耳蜗植入术的1至6岁儿童被随机分为对照组或MgSO组。主要结局指标为手术视野质量,次要结局指标为平均动脉压(MAP)、心率(HR)、ESRT及术中麻醉需求。同时记录不良事件的发生率。
M组的手术视野质量优于C组,P<0.02。达到最佳手术条件(评分≤2)的儿童数量,M组(23/33,70%)显著优于C组(13/33,39%),P<0.001。M组的MAP、HR及麻醉需求显著更低,P<0.05。两组在ESRT反应方面无差异。
在TIVA下进行的小儿人工耳蜗植入手术中,静脉输注硫酸镁可优化手术视野并降低麻醉需求,且不减弱ESRT。