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南非农村地区 5 岁以下儿童的家庭死亡:一项基于人群的纵向研究。

Home deaths of children under 5 years in rural South Africa: a population-based longitudinal study.

机构信息

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.

Department of Primary Care and Population Sciences, University of Southampton, Southampton, UK.

出版信息

Trop Med Int Health. 2019 Jul;24(7):862-878. doi: 10.1111/tmi.13239. Epub 2019 May 14.

Abstract

OBJECTIVES

To determine the proportion of under-5 deaths that occurred at home in rural South Africa, whether care was sought prior to death, and determinants of home deaths amongst those who sought care.

METHODS

Verbal autopsy data were used for all under-5 deaths, 2000-2015, in two health and demographic surveillance system sites. Trends in place of death and care-seeking were assessed. Associations between sociodemographic factors and home death despite seeking care were assessed by multivariate logistic regressions.

RESULTS

There were 3760 under-5 deaths; 1954 (53%) at home and 1510 (41%) in health facilities. Eighty-four per cent of children who died at home accessed healthcare during their final illness. Amongst neonates for whom care was sought, those who were 8-27 days old were more likely to die at home than those who were 0-7 days old (OR = 5.56, 95%CI 2.69-11.55, P < 0.001). Factors associated with home death of infants and young children despite seeking care included low maternal education (OR = 1.71, 95%CI 1.31-2.24, P < 0.001), larger household size (OR = 1.56, 95%CI 1.17-2.06, P = 0.002), traditional medicine use (OR = 2.33, 95%CI 1.75-3.12, P < 0.001) and Mozambican descent (OR = 1.47, 95%CI 1.06-2.03, P = 0.020). The proportion of HIV-related deaths that occurred at home fell from 60% in 2008-2011 to 39% in 2012-2015 ( χ  = 13.86, P < 0.001).

CONCLUSION

More than half of under-5 deaths in rural South Africa occurred at home although healthcare was sought for most children, highlighting that home deaths are not simply a function of poor care-seeking. Interventions should target high-risk sociodemographic groups.

摘要

目的

确定南非农村地区 5 岁以下儿童死亡中在家中死亡的比例,以及在家中死亡的儿童中是否在死亡前寻求过医疗护理,以及寻求过医疗护理的儿童中在家中死亡的决定因素。

方法

使用两个健康和人口监测系统站点的所有 2000-2015 年 5 岁以下儿童的死因推断数据。评估了死亡地点和寻求医疗护理的趋势。通过多变量逻辑回归评估了社会人口因素与在家中死亡(尽管寻求过医疗护理)之间的关联。

结果

共有 3760 名 5 岁以下儿童死亡;1954 人(53%)在家中,1510 人(41%)在医疗机构中。在家中死亡的 84%的儿童在其最后一次患病期间接受了医疗保健。在寻求医疗护理的新生儿中,8-27 天的婴儿比 0-7 天的婴儿更有可能在家中死亡(OR=5.56,95%CI 2.69-11.55,P<0.001)。尽管寻求了医疗护理,但与婴儿和幼儿在家中死亡相关的因素包括母亲受教育程度低(OR=1.71,95%CI 1.31-2.24,P<0.001),家庭规模较大(OR=1.56,95%CI 1.17-2.06,P=0.002),使用传统医学(OR=2.33,95%CI 1.75-3.12,P<0.001)和莫桑比克人后裔(OR=1.47,95%CI 1.06-2.03,P=0.020)。在家中发生的与 HIV 相关的死亡比例从 2008-2011 年的 60%下降到 2012-2015 年的 39%( χ ²=13.86,P<0.001)。

结论

南非农村地区超过一半的 5 岁以下儿童死亡发生在家中,尽管大多数儿童都寻求了医疗护理,这表明在家中死亡不仅仅是寻求医疗护理不佳的结果。干预措施应针对高危社会人口群体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04fd/7612936/b1577601a7a0/EMS146237-f001.jpg

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