Kocur G J, Drier E A, Simmons M J
Genetics. 1986 Dec;114(4):1147-63. doi: 10.1093/genetics/114.4.1147.
Inbred wild strains of Drosophila melanogaster derived from the central and eastern United States were used to make dysgenic hybrids in the P-M system. These strains possessed P elements and the P cytotype, the condition that represses P element transposition. Their hybrids were studied for the mutability of the P element insertion mutation, snw, and for the incidence of gonadal dysgenesis (GD) sterility. All the strains tested were able to induce hybrid dysgenesis by one or both of these assays; however, high levels of dysgenesis were rare. Sets of X chromosomes and autosomes from the inbred wild strains were more effective at inducing GD sterility than were sets of Y chromosomes and autosomes. In two separate analyses, GD sterility was positively correlated with snw mutability, suggesting a linear relationship. However, one strain appeared to induce too much GD sterility for its level of snw destabilization, indicating an uncoupling of these two manifestations of hybrid dysgenesis.
源自美国中部和东部的黑腹果蝇近交野生品系被用于构建P-M系统中的致育性杂种。这些品系拥有P因子和P细胞型，后者是抑制P因子转座的条件。对它们的杂种进行了P因子插入突变snw的突变率以及性腺发育不全（GD）不育发生率的研究。所有测试品系都能够通过这两种检测方法中的一种或两种诱导杂种致育性；然而，高程度的致育性很少见。近交野生品系的X染色体组和常染色体组在诱导GD不育方面比Y染色体组和常染色体组更有效。在两项独立分析中，GD不育与snw突变率呈正相关，表明存在线性关系。然而，有一个品系似乎因其snw不稳定程度而诱导了过多的GD不育，这表明杂种致育性的这两种表现形式出现了解耦。
