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果蝇中P因子转座所需的反式作用产物。

A trans-acting product needed for P factor transposition in Drosophila.

作者信息

Engels W R

出版信息

Science. 1984 Dec 7;226(4679):1194-6. doi: 10.1126/science.6095450.

DOI:10.1126/science.6095450
PMID:6095450
Abstract

A transposable genetic element of the P family in Drosophila melanogaster was found to be unstable in the presence of other P elements but stable in their absence. A sensitive assay for P transpositional activity is provided by the snw allele, a defective P insert in the singed bristle locus which becomes hypermutable only in the presence of complete elements. This measure of activity was highly correlated with a type of female sterility normally associated with P activity. There was no cross-reactivity with transposase from another hybrid dysgenesis-causing element (the I factor).

摘要

在果蝇中发现,P家族的一种转座遗传元件在存在其他P元件时不稳定,但在不存在其他P元件时稳定。snw等位基因提供了一种检测P转座活性的灵敏方法,snw等位基因是位于焦刚毛基因座上的一个有缺陷的P插入片段,它只有在存在完整元件时才会发生高频突变。这种活性测量与通常与P活性相关的一种雌性不育类型高度相关。它与另一种导致杂种不育的元件(I因子)的转座酶没有交叉反应。

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