Sezen Celal Bugra, Bilen Salih, Kalafat Cem Emrah, Cansever Levent, Sonmezoglu Yaşar, Kilimci Umut, Dogru Mustafa Vedat, Seyrek Yunus, Kocaturk Celalettin Ibrahim
Department of Thoracic Surgery, Yedikule Chest Diseases and Thoracic Surgery Education and Research Hospital, Istanbul, Turkey.
Department of Thoracic Surgery, Mardin State Hospital, 34020, Mardin, Turkey.
Gen Thorac Cardiovasc Surg. 2019 Nov;67(11):969-975. doi: 10.1007/s11748-019-01127-1. Epub 2019 Apr 19.
The aim of this study was to discuss indications and outcomes for conversion to thoracotomy during thoracoscopic lobectomy.
Patients who underwent lobectomy for non-small cell lung cancer between January 2012 and December 2016 were evaluated retrospectively. The study included 129 patients who underwent video-assisted thoracoscopic lobectomy (group-V) and 18 patients converted from thoracoscopic lobectomy to thoracotomy due to unexpected intraoperative complications (group-T).
The two patient groups showed no statistical differences in terms of demographic characteristics. Causes of unexpected conversions to thoracotomy were hemorrhage in six patients, dense pleural adhesions in seven patients, fused fissure in one patient, and fibrocalcified lymph nodes around the vascular structures in four patients. Operative time was 180.37 ± 68.6 min in group-V and 235 ± 72.6 min in group-T (p = 0.003). Intraoperative blood loss was 263.9 ± 180.6 mL in group-V, compared to 562.7 ± 296.2 mL in group-T (p < 0.001). Patient age ≥ 70 years was a significant risk factor for conversion to thoracotomy (p = 0.015, odds ratio 4.73). The 5-year survival rate in group-V was 71.4% {mean: 65.2 months [95% confidence interval (CI) 59.6-70.8]}, while that in group-T was 80% [mean 54.9 months (95% CI 45.9-63.8)] (p = 0.548).
Advanced age was identified as the main risk factor for conversion to thoracotomy. However, early- and long-term outcomes were similar in the two groups, indicating that video-assisted thoracoscopic surgery is a safe and applicable method.
本研究旨在探讨电视胸腔镜肺叶切除术中中转开胸的指征及结果。
回顾性评估2012年1月至2016年12月期间因非小细胞肺癌接受肺叶切除术的患者。该研究包括129例行电视辅助胸腔镜肺叶切除术的患者(V组)和18例因术中意外并发症由电视胸腔镜肺叶切除术中转开胸的患者(T组)。
两组患者在人口统计学特征方面无统计学差异。中转开胸的意外原因包括6例出血、7例致密胸膜粘连、1例融合裂以及4例血管结构周围纤维钙化淋巴结。V组手术时间为180.37±68.6分钟,T组为235±72.6分钟(p = 0.003)。V组术中失血量为263.9±180.6毫升,T组为562.7±296.2毫升(p < 0.001)。患者年龄≥70岁是中转开胸的显著危险因素(p = 0.015,比值比4.73)。V组5年生存率为71.4%(平均:65.2个月[95%置信区间(CI)59.6 - 70.8]),而T组为80%[平均54.9个月(95%CI 45.9 - 63.8)](p = 0.548)。
高龄被确定为中转开胸的主要危险因素。然而,两组的早期和长期结果相似,表明电视辅助胸腔镜手术是一种安全且适用的方法。