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一例与抗利尿激素分泌不当综合征相关的胸腺神经母细胞瘤病例报告:手术治疗后的十年随访结果

A case report of a thymic neuroblastoma associated with syndrome of inappropriate secretion of antidiuretic hormone: Ten-year follow-up results after surgical treatment.

作者信息

Satoh Yukitoshi

机构信息

Department of Thoracic Surgery, Kitasato University School of Medicine, 1-15-1 Kitasato, Minami-ku, Sagamihara-shi, Kanagawa 252-0374, Japan.

出版信息

Int J Surg Case Rep. 2019;58:45-47. doi: 10.1016/j.ijscr.2019.03.056. Epub 2019 Apr 5.

DOI:10.1016/j.ijscr.2019.03.056
PMID:31005046
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6476796/
Abstract

INTRODUCTION

Thymic neuroblastoma with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in adults is an extremely rare and malignant neoplasm. Although the tumor is known to grow rapidly and have a poor prognosis, its etiology is still uncertain. In 2009, we described a case of thymic neuroblastoma with SIADH. We report here the clinical course over the last 10 years.

PRESENTATION OF CASE

A 70-year-old Japanese male with a history of thymic neuroblastoma with SIADH was regularly followed up on an out-patient basis after complete surgical resection for more than 10 years. He remains free of the disease and asymptomatic.

DISCUSSION AND CONCLUSION

Complete surgical removal is considered as one of the treatment options for this tumor if clearly separated from the surrounding tissue with no invasion.

摘要

引言

成人胸腺神经母细胞瘤伴抗利尿激素分泌异常综合征(SIADH)是一种极其罕见的恶性肿瘤。尽管已知该肿瘤生长迅速且预后较差,但其病因仍不明确。2009年,我们报道了一例伴有SIADH的胸腺神经母细胞瘤病例。在此,我们报告该病例过去10年的临床病程。

病例介绍

一名70岁日本男性,有胸腺神经母细胞瘤伴SIADH病史,在完整手术切除后门诊定期随访超过10年。他仍无疾病且无症状。

讨论与结论

如果能与周围组织清晰分离且无侵犯,完整手术切除被认为是该肿瘤的治疗选择之一。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7db/6476796/94f67804e0d3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7db/6476796/94f67804e0d3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7db/6476796/94f67804e0d3/gr1.jpg

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