Department of Urology, Jichi Medical University, Tochigi, Japan; The Japanese Research Group for Urinary Tract Infection (JRGU), Japan.
Yazawa Clinic, Tokyo, Japan; Department of Urology, Keio University, School of Medicine, Tokyo, Japan; The Japanese Research Group for Urinary Tract Infection (JRGU), Japan.
J Infect Chemother. 2019 Jul;25(7):567-570. doi: 10.1016/j.jiac.2019.03.024. Epub 2019 Apr 17.
We performed a questionnaire-based, retrospective, nationwide survey on perioperative management and antimicrobial prophylaxis for mid-urethral sling surgery for stress urinary incontinence in Japan to realize the clinical practice and risk factors for SSI. Records of women receiving transobturator tape (TOT) and tension-free vaginal tape (TVT) surgeries from 2010 to 2012 were obtained from hospitals belonging to the Japanese Society of Pelvic Organ Prolapse Surgery. The questionnaire addressed hospital volume, perioperative management, and SSI. Risk factors for SSI were investigated by comparing cases with and without SSI. The data from 97 hospitals and a total 1627 TOT and 1045 TVT surgeries were analyzed. Mean case volumes of TOT and TVT surgeries were 7.3 ± 14.9 and 7.1 ± 17.8 cases per year, respectively. Preoperative hair removal, bowel preparation, and urine culture were routinely performed at 44 (45.3%), 31 (32.0%), and 22 (22.7%) hospitals, respectively. First-generation (51.5%) or second-generation (34.0%) cephalosporin was mostly used for antimicrobial prophylaxis. SSI was reported only in 6 patients (0.22%) and none of them developed abscesses. None of the factors we could evaluate from the questionnaire were found to be significantly associated with SSI. SSI after mid-urethral slings rarely occurred in Japan (0.22%) and no parameters about perioperative managements significantly increased SSI. However, further studies with more detail information of each patient and operation are required to confirm their appropriate perioperative managements for mid-urethral slings.
我们在日本针对压力性尿失禁行尿道中段悬吊术(mid-urethral sling surgery)的围手术期管理和抗菌预防进行了一项基于问卷调查的回顾性全国性研究,以了解手术部位感染(SSI)的临床实践和危险因素。从日本盆腔器官脱垂学会(Japanese Society of Pelvic Organ Prolapse Surgery)所属医院获取了 2010 年至 2012 年接受经闭孔吊带(transobturator tape,TOT)和阴道无张力吊带(tension-free vaginal tape,TVT)手术的女性记录。问卷涉及医院数量、围手术期管理和 SSI。通过比较有和无 SSI 的病例,调查了 SSI 的危险因素。分析了 97 家医院的资料和总共 1627 例 TOT 和 1045 例 TVT 手术。TOT 和 TVT 手术的平均病例量分别为每年 7.3±14.9 和 7.1±17.8 例。分别有 44 家(45.3%)、31 家(32.0%)和 22 家(22.7%)医院常规进行术前备皮、肠道准备和尿培养。第一代(51.5%)或第二代(34.0%)头孢菌素类抗生素大多用于抗菌预防。仅报告了 6 例(0.22%)SSI,均未形成脓肿。问卷调查中我们能够评估的因素均与 SSI 无显著相关性。日本尿道中段吊带术后 SSI 发生率较低(0.22%),没有任何围手术期管理参数显著增加 SSI。然而,需要进一步研究,以获得有关每位患者和手术的更详细信息,以确认尿道中段吊带术的合适围手术期管理。