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髓系肉瘤在新诊断的急性髓系白血病中表现为双侧急性外耳道炎。

Myeloid sarcoma presenting as bilateral acute otitis externa in newly diagnosed acute myeloid leukemia.

作者信息

Chen Sarah M, Silverman Dustin A, Jatana Kris R, Chiang Tendy, Guinipero Terri, Hill Nina, Siu Jason J, Reed Suzanne

机构信息

Division of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, OH, USA.

Department of Otolaryngology - Head & Neck Surgery, Nationwide Children's Hospital, Wexner Medical Center at Ohio State University, Columbus, OH, USA.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 Jul;122:126-129. doi: 10.1016/j.ijporl.2019.04.002. Epub 2019 Apr 3.

DOI:10.1016/j.ijporl.2019.04.002
PMID:31005747
Abstract

Myeloid sarcoma (MS) is an extramedullary collection of immature myeloid cells that can commonly occur with acute myeloid leukemia (AML). While head and neck presentations are not unheard of, there have been few published pediatric cases of external auditory canal MS. Here, we report a case of a 14-year-old male who presented with MS masquerading as bilateral acute otitis externa. To the best of our knowledge, this is the first reported case of a bilateral presentation leading to a new diagnosis of AML. A literature review of head and neck presentations of MS is included.

摘要

髓系肉瘤(MS)是未成熟髓系细胞的髓外聚集,常与急性髓系白血病(AML)同时发生。虽然头颈部表现并非罕见,但关于外耳道MS的儿科病例报道很少。在此,我们报告一例14岁男性,其表现为伪装成双侧急性外耳道炎的MS。据我们所知,这是首例因双侧表现而新诊断为AML的病例。本文还包括了对MS头颈部表现的文献综述。

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引用本文的文献

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Patient cases with malignant otitis externa at the university clinic of Ludwig Maximilians University Munich from 2009 until 2020.2009年至2020年期间,慕尼黑路德维希·马克西米利安大学大学诊所收治的恶性外耳道炎患者病例。
Sci Rep. 2025 Jul 21;15(1):26367. doi: 10.1038/s41598-025-11742-z.
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Myeloid Sarcoma: Novel Advances Regarding Molecular Pathogenesis, Presentation and Therapeutic Options.髓系肉瘤:关于分子发病机制、临床表现及治疗选择的新进展
J Clin Med. 2024 Oct 16;13(20):6154. doi: 10.3390/jcm13206154.