Chen Sarah M, Silverman Dustin A, Jatana Kris R, Chiang Tendy, Guinipero Terri, Hill Nina, Siu Jason J, Reed Suzanne
Division of Hematology/Oncology/BMT, Nationwide Children's Hospital, Columbus, OH, USA.
Department of Otolaryngology - Head & Neck Surgery, Nationwide Children's Hospital, Wexner Medical Center at Ohio State University, Columbus, OH, USA.
Int J Pediatr Otorhinolaryngol. 2019 Jul;122:126-129. doi: 10.1016/j.ijporl.2019.04.002. Epub 2019 Apr 3.
Myeloid sarcoma (MS) is an extramedullary collection of immature myeloid cells that can commonly occur with acute myeloid leukemia (AML). While head and neck presentations are not unheard of, there have been few published pediatric cases of external auditory canal MS. Here, we report a case of a 14-year-old male who presented with MS masquerading as bilateral acute otitis externa. To the best of our knowledge, this is the first reported case of a bilateral presentation leading to a new diagnosis of AML. A literature review of head and neck presentations of MS is included.
髓系肉瘤(MS)是未成熟髓系细胞的髓外聚集,常与急性髓系白血病(AML)同时发生。虽然头颈部表现并非罕见,但关于外耳道MS的儿科病例报道很少。在此,我们报告一例14岁男性,其表现为伪装成双侧急性外耳道炎的MS。据我们所知,这是首例因双侧表现而新诊断为AML的病例。本文还包括了对MS头颈部表现的文献综述。