伊伐布雷定是治疗非典型直立性心动过速综合征的神奇药物吗？
Is ivabradine a wonder drug for atypical POTS?
作者信息
Cheema Muhammad Arslan, Zain Muhammad Abdullah, Ullah Waqas, Cheema Khadija
机构信息
Internal Medicine, Abington Hospital - Jefferson Health, Abington, PA, USA.
Internal Medicine, Sheikh Zayed Medical College, Rahim Yar Khan, Pakistan.
出版信息
BMJ Case Rep. 2019 Apr 20;12(4):e227789. doi: 10.1136/bcr-2018-227789.
Abstract
Syncope is a sudden loss and gain of consciousness. Traditionally, it is caused by the abnormalities of neurological, cardiac or vasovagal systems. We present a case of a 19-year-old woman presenting with recurrent syncopal episodes with no apparent cause. Examination and investigations were unremarkable for any aetiology except positive tilt tests for postural orthostatic tachycardia syndrome. The purpose of this report is to make physicians aware of the unique presentation of this rare aetiology with recurrent syncopal episodes and the novel management approach.
摘要
晕厥是一种意识的突然丧失和恢复。传统上，它是由神经、心脏或血管迷走神经等系统的异常引起的。我们报告一例19岁女性，反复出现不明原因的晕厥发作。除直立倾斜试验对体位性直立性心动过速综合征呈阳性外，检查和各项调查均未发现任何病因。本报告的目的是让医生了解这种罕见病因伴有反复晕厥发作的独特表现以及新颖的管理方法。
相似文献
1
Is ivabradine a wonder drug for atypical POTS?伊伐布雷定是治疗非典型直立性心动过速综合征的神奇药物吗？
BMJ Case Rep. 2019 Apr 20;12(4):e227789. doi: 10.1136/bcr-2018-227789.
2
Postural Orthostatic Tachycardia Syndrome and Vasospastic Angina: Therapeutic Approach to a Previously Unreported Association.体位性直立性心动过速综合征与血管痉挛性心绞痛：一种此前未报道关联的治疗方法。
Rev Esp Cardiol (Engl Ed). 2019 Jun;72(6):509-510. doi: 10.1016/j.rec.2018.05.043. Epub 2018 Oct 12.
3
Confounders of vasovagal syncope: postural tachycardia syndrome.血管迷走性晕厥的混杂因素：体位性心动过速综合征。
Cardiol Clin. 2013 Feb;31(1):101-9. doi: 10.1016/j.ccl.2012.09.004.
4
[Postural orthostatic tachycardia syndrome (POTS): report of 15 cases].[体位性直立性心动过速综合征（POTS）：15例报告]
Rev Med Chil. 2012 Feb;140(2):145-52. doi: 10.4067/S0034-98872012000200001.
5
Randomized Trial of Ivabradine in Patients With Hyperadrenergic Postural Orthostatic Tachycardia Syndrome.随机试验伊伐布雷定在高肾上腺素能体位性心动过速综合征患者。
J Am Coll Cardiol. 2021 Feb 23;77(7):861-871. doi: 10.1016/j.jacc.2020.12.029.
6
Atrioventricular node ablation and pacemaker implantation for recurrent syncope in a patient with postural tachycardia syndrome (POTS).房室结消融联合起搏器植入治疗体位性心动过速综合征（POTS）患者的反复晕厥。
J Cardiovasc Electrophysiol. 2011 Nov;22(11):1284-7. doi: 10.1111/j.1540-8167.2011.02078.x. Epub 2011 May 3.
7
Successful use of ivabradine in a case of exaggerated autonomic dysfunction.伊伐布雷定在一例自主神经功能障碍过度病例中的成功应用。
Turk Kardiyol Dern Ars. 2010 Jun;38(4):285-9.
8
Ivabradine for the Treatment of Postural Orthostatic Tachycardia Syndrome: A Systematic Review.伊伐布雷定治疗体位性心动过速综合征：系统评价。
Am J Cardiovasc Drugs. 2018 Jun;18(3):195-204. doi: 10.1007/s40256-017-0252-1.
9
Orthostatic intolerance: postural orthostatic tachycardia syndrome with overlapping vasovagal syncope.直立不耐受：伴有重叠血管迷走性晕厥的体位性直立性心动过速综合征。
Acta Clin Croat. 2012 Mar;51(1):93-5.
10
Ivabradine in Postural Orthostatic Tachycardia Syndrome: Preliminary Experience in Children.直立性心动过速综合征中伊伐布雷定的应用：儿童初步经验。
Am J Cardiovasc Drugs. 2018 Feb;18(1):59-63. doi: 10.1007/s40256-017-0248-x.
引用本文的文献
1
COVID-19 Induced Postural Orthostatic Tachycardia Syndrome (POTS): A Review.新冠病毒感染所致体位性直立性心动过速综合征（POTS）：综述
Cureus. 2023 Mar 31;15(3):e36955. doi: 10.7759/cureus.36955. eCollection 2023 Mar.
2
Ivabradine use in pregnant women-treatment indications and pregnancy outcome: an evaluation of the German Embryotox database.依伐布雷定在孕妇中的应用-治疗指征和妊娠结局：德国胚胎毒性数据库评估。
Eur J Clin Pharmacol. 2021 Jul;77(7):1029-1037. doi: 10.1007/s00228-020-03066-w. Epub 2021 Jan 26.
3
Ivabradine in Postural Orthostatic Tachycardia Syndrome: A Review of the Literature.伊伐布雷定在体位性直立性心动过速综合征中的应用：文献综述
Cureus. 2020 Apr 28;12(4):e7868. doi: 10.7759/cureus.7868.
本文引用的文献
1
Postural Orthostatic Tachycardia Syndrome and Its Unusual Presenting Complaints in Women: A Literature Minireview.体位性直立性心动过速综合征及其在女性中不寻常的主诉：文献综述
Cureus. 2018 Apr 5;10(4):e2435. doi: 10.7759/cureus.2435.
2
Cerebral Blood Flow, Heart Rate, and Blood Pressure Patterns during the Tilt Test in Common Orthostatic Syndromes.常见体位性综合征倾斜试验期间的脑血流量、心率和血压模式。
Neurosci J. 2016;2016:6127340. doi: 10.1155/2016/6127340. Epub 2016 Jul 20.
3
2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope.2015年心律协会关于体位性心动过速综合征、不适当窦性心动过速和血管迷走性晕厥诊断与治疗的专家共识声明
Heart Rhythm. 2015 Jun;12(6):e41-63. doi: 10.1016/j.hrthm.2015.03.029. Epub 2015 May 14.
4
POTS following traumatic stress: interacting central and intracardiac neural control?
J Diabetes Complications. 2015 Apr;29(3):459-61. doi: 10.1016/j.jdiacomp.2015.02.003. Epub 2015 Feb 13.
5
Neuronal and hormonal perturbations in postural tachycardia syndrome.体位性心动过速综合征中的神经和激素紊乱。
Front Physiol. 2014 Jun 16;5:220. doi: 10.3389/fphys.2014.00220. eCollection 2014.
6
Postural orthostatic tachycardia syndrome (POTS).体位性直立性心动过速综合征（POTS）。
BMJ Case Rep. 2013 Sep 16;2013:bcr2013201244. doi: 10.1136/bcr-2013-201244.
7
Atrioventricular node ablation and pacemaker implantation for recurrent syncope in a patient with postural tachycardia syndrome (POTS).房室结消融联合起搏器植入治疗体位性心动过速综合征（POTS）患者的反复晕厥。
J Cardiovasc Electrophysiol. 2011 Nov;22(11):1284-7. doi: 10.1111/j.1540-8167.2011.02078.x. Epub 2011 May 3.
8
Single centre experience of ivabradine in postural orthostatic tachycardia syndrome.体位性心动过速综合征中伊伐布雷定的单中心经验。
Europace. 2011 Mar;13(3):427-30. doi: 10.1093/europace/euq390. Epub 2010 Nov 9.
9
Successful use of ivabradine in a case of exaggerated autonomic dysfunction.伊伐布雷定在一例自主神经功能障碍过度病例中的成功应用。
Turk Kardiyol Dern Ars. 2010 Jun;38(4):285-9.
10
Treatment of inappropriate sinus tachycardia with ivabradine in a patient with postural orthostatic tachycardia syndrome and a dual chamber pacemaker.伊伐布雷定治疗体位性直立性心动过速综合征合并双腔起搏器患者的不适当窦性心动过速
Pacing Clin Electrophysiol. 2009 Jan;32(1):131-3. doi: 10.1111/j.1540-8159.2009.02186.x.
Zotero 插件