Liao Y, Yi Y, Lin X, Hao Y T
Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China; Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2019 Apr 10;40(4):406-411. doi: 10.3760/cma.j.issn.0254-6450.2019.04.007.
To estimate the health-related quality of life (HRQOL) and health-adjusted life expectancy (HALE) which were associated with chronic non-communicable diseases (NCDs) in people from Guangdong province of China. Data on both NCDs prevalence and EuroQol-5 Dimensions-3 Levels measured HRQOL were gathered from the Fifth National Health Survey in Guangdong province, 2013. Logistic regression model and multiple linear regression model were employed to explore the impact of NCDs on HRQOL. Life expectancy (LE) and HALE were used to evaluate the comprehensive impact of chronic diseases on population health. A total of 68 550 inhabitants were included in the analysis. Graded logistic regression showed that the impact of chronic diseases on all dimensions of quality of life was statistically significant after adjusting for social demographic characteristics. The greatest health impact was on the pain/discomfort health dimension [=4.48 (95:4.20-4.77)], followed by anxiety/depression[=3.95 (95: 3.62- 4.31)], daily activities [=3.69 (95: 3.37-4.04)], mobility [=3.63 (95: 3.34-3.94)]and ability on self-care [=3.30 (95: 2.98-3.66)]. Losses of LE and HALE caused by NCDs were 12.7 and 14.6 years respectively while the overall expected gain was 3.8 years in HALE, when NCDs were taken away. Our data showed that NCDs had shortened the healthy life span of patients through reducing the HRQOL and also causing heavy disease burden on both patients with NCDs and the communities. Health-care related policies on NCDs need to be developed, for the elderly, in particular.
评估中国广东省人群中与慢性非传染性疾病（NCDs）相关的健康相关生活质量（HRQOL）和健康调整生命预期（HALE）。2013年广东省第五次全国卫生调查收集了有关非传染性疾病患病率以及采用欧洲五维度健康量表（EuroQol-5 Dimensions-3 Levels）测量的健康相关生活质量的数据。采用逻辑回归模型和多元线性回归模型来探究非传染性疾病对健康相关生活质量的影响。采用预期寿命（LE）和健康调整生命预期来评估慢性病对人群健康的综合影响。共有68550名居民纳入分析。分级逻辑回归显示，在调整社会人口学特征后，慢性病对生活质量各维度的影响具有统计学意义。对健康影响最大的是疼痛/不适健康维度[=4.48（95%置信区间：4.20-4.77）]，其次是焦虑/抑郁[=3.95（95%置信区间：3.62-4.31）]、日常活动[=3.69（95%置信区间：3.37-4.04）]、行动能力[=3.63（95%置信区间：3.34-3.94）]和自我护理能力[=3.30（95%置信区间：2.98-3.66）]。当去除非传染性疾病时，非传染性疾病导致的预期寿命和健康调整生命预期损失分别为12.7年和14.6年，而健康调整生命预期的总体预期增益为3.8年。我们的数据表明，非传染性疾病通过降低健康相关生活质量缩短了患者的健康寿命，同时也给非传染性疾病患者及其社区带来了沉重的疾病负担。尤其需要针对老年人制定与非传染性疾病相关的医疗保健政策。
