Department of Chronic Disease Control, Wuxi Center for Disease Control and Prevention, Wuxi, China.
Front Public Health. 2022 Jul 18;10:925114. doi: 10.3389/fpubh.2022.925114. eCollection 2022.
This study aims to investigate sex, age, and cause-specific contributions to changes and trend disparities in life expectancy (LE) and health-adjusted life expectancy (HALE) attributed to disability and mortality from 1990 to 2019 in China, which provides insight into policy-making, health systems planning, and resource allocation.
Contributions of disability and mortality to changes and trend disparities in LE and HALE were estimated with standard abridged life table, Sullivan's method, and decomposition method, using retrospective demographic analysis based on mortality and years lived with disability (YLD) rates extracted from Global Burden of Disease Study 2019 (GBD 2019).
From 1990 to 2019, LE and HALE increased by 10.49 and 8.71 years for both sexes, mainly due to noncommunicable diseases (NCDs) (5.83 years, 55.58% for LE and 6.28 years, 72.10% for HALE). However, HIV/AIDS and sexually transmitted infections had negative effects on changes in LE (-0.03 years, -0.29%) and HALE (-0.05 years, -0.57%). Lung cancer and ischemic heart disease caused the biggest reduction in LE (-0.14 years, -1.33%) and HALE (-0.42 years, -4.82%). Also, cardiovascular diseases (-0.08 years, -0.92%), neurological disorders (-0.08 years, -0.92%), diabetes and kidney diseases (-0.06 years, -0.69%), and transport injuries (-0.06 years, -0.69%) had main negative disability effects in HALE. Moreover, life expectancy lived with disability (LED) increased by 1.78 years, mainly attributed to respiratory infections and tuberculosis (1.04 years, 58.43%) and maternal and neonatal disorders (0.78 years, 43.82%).
The LE and HALE in China have grown rapidly over the past few decades, mainly attributed to NCDs. It is necessary to further reduce the negative mortality effect of HIV/AIDS, lung cancer, colon and rectum cancer, pancreatic cancer, and ischemic heart disease and the negative disability effect of stroke, diabetes mellitus, and road injuries. In addition, the signs of disparities in mortality and disability of different sexes and ages call for targeted and precise interventions for key groups such as males and the elderly. According to the decomposition results, we may better determine the key objects of health policies that take into account substantial cause-specific variations to facilitate the realization of "healthy China 2030" plan.
本研究旨在探讨性别、年龄以及由残疾和死亡导致的预期寿命(LE)和健康调整预期寿命(HALE)变化和趋势差异的决定因素,为政策制定、卫生系统规划和资源分配提供依据。
利用死亡率和伤残所致失能年(YLD)率从全球疾病负担研究 2019 年(GBD 2019)中提取的数据,采用标准简略生命表、沙利文法和分解法,对 1990 年至 2019 年残疾和死亡对 LE 和 HALE 变化和趋势差异的贡献进行估计。
1990 年至 2019 年,两性 LE 和 HALE 均增加了 10.49 岁和 8.71 岁,主要归因于非传染性疾病(NCDs)(LE 增加 5.83 岁,占 55.58%;HALE 增加 6.28 岁,占 72.10%)。然而,艾滋病毒/艾滋病和性传播感染对 LE(-0.03 岁,-0.29%)和 HALE(-0.05 岁,-0.57%)的变化产生了负面影响。肺癌和缺血性心脏病导致 LE(-0.14 岁,-1.33%)和 HALE(-0.42 岁,-4.82%)降幅最大。此外,心血管疾病(-0.08 岁,-0.92%)、神经障碍(-0.08 岁,-0.92%)、糖尿病和肾脏疾病(-0.06 岁,-0.69%)以及交通伤害(-0.06 岁,-0.69%)对 HALE 造成了主要的负面残疾影响。此外,伤残预期寿命(LED)增加了 1.78 岁,主要归因于呼吸道感染和结核病(1.04 岁,占 58.43%)和孕产妇及新生儿疾病(0.78 岁,占 43.82%)。
中国在过去几十年中 LE 和 HALE 迅速增长,主要归因于 NCDs。有必要进一步降低艾滋病毒/艾滋病、肺癌、结肠癌和直肠癌、胰腺癌和缺血性心脏病的死亡负效应以及中风、糖尿病和道路伤害的残疾负效应。此外,不同性别和年龄的死亡率和残疾率差异的迹象表明,需要针对男性和老年人等关键群体采取有针对性和精确的干预措施。根据分解结果,我们可以更好地确定考虑到实质性病因特异性变化的卫生政策的重点对象,以促进“健康中国 2030”计划的实现。