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青春期摄入不同种类的白葡萄汁(Vitis labrusca)对成年 Wistar 大鼠体重、生化参数和肝脏氧化应激的影响。

Effects of the ingestion of different kinds of white grape juice (Vitis labrusca) during adolescence on body weight, biochemical parameters and oxidative stress in liver of adult Wistar rats.

机构信息

Laboratory of Biochemistry of Centro Universitário Metodista IPA, Porto Alegre, Rio Grande do Sul, Brazil.

Laboratory of Biochemistry of Centro Universitário Metodista IPA, Porto Alegre, Rio Grande do Sul, Brazil.

出版信息

Food Chem. 2019 Sep 1;291:110-116. doi: 10.1016/j.foodchem.2019.03.122. Epub 2019 Mar 25.

Abstract

The objective of this study was to evaluate the effects of the ingestion of different white grape juices: organic, conventional and conventional grape juice with 5% lemon juice during adolescence on biochemical serum profile and oxidative stress level in liver of adult Wistar rats. The phenolic and vitamin C composition of the juices were evaluated. During 32 days the rats were treated with the juices or oral water (gavage) for at a dose of 7 μL/g body weight. The animals were divided into 4 groups (n = 16/each). In the end, half of the animals received an intraperitoneal CCl injection of 3.0 mL/kg; the other ones received mineral oil. After euthanasia, biochemical parameters were evaluated in serum and oxidative stress in the liver. It is possible to emphasize that the juices have different phenolic and vitamin C contents. The juice consumption didn't alter the weight body and biochemical parameters in adult life.

摘要

本研究旨在评估青春期摄入不同白葡萄汁(有机、传统和传统葡萄汁添加 5%柠檬汁)对成年 Wistar 大鼠血清生化谱和肝脏氧化应激水平的影响。评估了果汁的酚类和维生素 C 组成。在 32 天的时间里,老鼠通过灌胃的方式接受剂量为 7μL/g 体重的果汁或口服水的处理。动物被分为 4 组(每组 16 只)。最后,一半的动物接受了 3.0 mL/kg 的腹腔内 CCl 注射;另一半则接受了矿物油。安乐死后,评估血清中的生化参数和肝脏中的氧化应激。可以强调的是,果汁具有不同的酚类和维生素 C 含量。果汁的摄入并没有改变成年后的体重和生化参数。

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