衰老个体中与髓系恶性肿瘤相关的体细胞突变。
Myeloid malignancies-related somatic mutations in aging individuals.
机构信息
Laboratório de Biologia Molecular, Centro de Transplante de Medula Óssea, Instituto Nacional de Câncer, Rio de Janeiro, Brazil.
Perlmutter Cancer Center, New York University Langone Health, New York, New York.
出版信息
Mol Genet Genomic Med. 2019 Jun;7(6):e683. doi: 10.1002/mgg3.683. Epub 2019 Apr 21.
Abstract
We search for the presence of somatic mutations in 12 genes related to MDS, MPN, and AML in a Brazilian cohort composed of 609 elderly individuals from a census-based sample.
摘要
我们在一个基于人口普查样本的 609 名巴西老年人群体中寻找与 MDS、MPN 和 AML 相关的 12 个基因的体细胞突变。
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