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澳大利亚育龄期女性的慢性疼痛、疼痛严重程度和镇痛药物使用情况。

Chronic pain, pain severity and analgesia use in Australian women of reproductive age.

机构信息

Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.

Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia; School of Health Sciences, University of East Anglia, Norwich, UK.

出版信息

Women Birth. 2019 Apr;32(2):e272-e278. doi: 10.1016/j.wombi.2018.06.013. Epub 2018 Jul 7.

Abstract

BACKGROUND

The increasing prevalence and adverse outcomes associated with opioid analgesia use in women of reproductive age have become a significant public health issue internationally, with use during pregnancy potentially affecting maternal and infant health outcomes.

OBJECTIVE

This study aims to provide national estimates of chronic pain, pain severity and analgesia use in Australian women of reproductive age by pregnancy status.

METHOD

Data were obtained from the Australian Bureau of Statistics 2011-12 National Health Survey (n=20,426). Weighting was applied to sample data to obtain population estimates. For this study data were analysed for pregnant (n=166, N=192,617) and non-pregnant women (n=4710, N=5,256,154) of reproductive age (15-49 years).

RESULTS

Chronic or reoccurring pain was reported in 5.1% of pregnant women and 9.7% of non-pregnant women, and 0.7% and 2.6% of pregnant and non-pregnant women reported recent opioid analgesia use respectively. Moderate-to-very severe pain was more common in pregnant than non-pregnant women taking opioid analgesics, and no pain and very mild-to-mild pain in non-pregnant women.

CONCLUSION

Approximately 1 in 20 pregnant Australian women have chronic or reoccurring pain. Opioid analgesia was used by around 1% of Australian pregnant women during a two-week period, with use associated with moderate-to-very severe pain. Given that the safety of many analgesic medications in pregnancy remains unknown, pregnant women and health professionals require accurate, up-to-date information on the risks and benefits of analgesic use during pregnancy. Further evidence on the decision-making processes of pregnant women with pain should assist health professionals maximise outcomes for mothers and infants.

摘要

背景

在育龄妇女中,阿片类镇痛药的使用日益普遍,且相关不良后果不断增加,这已成为一个国际性的重大公共卫生问题,而怀孕期间的使用可能会影响母婴健康结局。

目的

本研究旨在根据妊娠状况,估算澳大利亚育龄期女性的慢性疼痛、疼痛严重程度和镇痛药使用情况的全国数据。

方法

数据来自澳大利亚统计局 2011-12 年国家健康调查(n=20426)。对样本数据进行加权处理,以获取人口估计值。本研究分析了妊娠(n=166,N=192617)和非妊娠(n=4710,N=5256154)育龄期(15-49 岁)女性的数据。

结果

报告称,5.1%的孕妇和 9.7%的非孕妇患有慢性或复发性疼痛,分别有 0.7%和 2.6%的孕妇和非孕妇最近使用过阿片类镇痛药。使用阿片类镇痛药的孕妇中,中度至重度疼痛更为常见,而非孕妇中则是无疼痛和轻度至轻度疼痛更为常见。

结论

大约每 20 名澳大利亚孕妇中就有 1 名患有慢性或复发性疼痛。约有 1%的澳大利亚孕妇在两周内使用过阿片类镇痛药,且该用药与中度至重度疼痛有关。鉴于许多镇痛药物在妊娠期间的安全性仍不明确,孕妇和卫生保健专业人员需要获得关于妊娠期间使用镇痛药的风险和益处的准确、最新信息。关于有疼痛的孕妇决策过程的进一步证据,将有助于卫生保健专业人员使母婴的结局最大化。

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