Sebastian Ivy Anne, Pandian Jeyaraj Durai, Oberoi Aroma, Kate Mahesh Pundlik, Jaison Vineeth, Bose Smriti, Sahonta Rajeshwar, Nagpal Shavi, Brar Indira
Department of Neurology, Christian Medical College, Ludhiana, Punjab, India.
Department of Microbiology, Christian Medical College, Ludhiana, Punjab, India.
Ann Indian Acad Neurol. 2019 Apr-Jun;22(2):234-237. doi: 10.4103/aian.AIAN_321_18.
(SS) is one of the most overlooked helminthic infections despite being highly endemic in tropical and subtropical areas. In immunocompromised patients, especially those on long-term steroids, infection can often escalate to fatal dissemination into major organs. We present a compendium of two immunocompromised patients, who were on high-dose steroids and presented with worsening neurological status. Cerebrospinal fluid analysis was notable for larvae of SS as diagnosed by direct visualization. A syndrome of SS hyperinfection with dissemination was made after stool, and sputum samples also revealed SS larvae. SS is an elusive disease and should be considered early on, especially in endemic regions like India. Early diagnosis and prompt initiation of antihelminthic therapy is indispensable for favorable outcomes.
类圆线虫病（SS）是最易被忽视的蠕虫感染之一，尽管在热带和亚热带地区高度流行。在免疫功能低下的患者中，尤其是长期使用类固醇的患者，感染往往会升级为致命性播散至主要器官。我们报告了两名免疫功能低下患者的病例集，他们均使用高剂量类固醇，并出现神经功能状态恶化。脑脊液分析显示直接观察到类圆线虫幼虫，这一点值得注意。粪便和痰液样本也发现了类圆线虫幼虫，从而诊断为类圆线虫超感染播散综合征。类圆线虫病是一种难以捉摸的疾病，应尽早考虑，尤其是在印度等流行地区。早期诊断并及时开始抗蠕虫治疗对于取得良好疗效必不可少。
