Pandey Rajendra Kumar, Jain Rohit Kumar, Hussain Syed Zammeer
Department of Neurology, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India.
Department of Medicine, Teerthanker Mahaveer Medical College and Research Centre, Moradabad, Uttar Pradesh, India.
Ann Indian Acad Neurol. 2019 Apr-Jun;22(2):240-241. doi: 10.4103/aian.AIAN_253_18.
Pharyngeal-cervical-brachial (PCB) variant is a rare localized variant of Guillain-Barré syndrome that presents with a rapidly progressive oropharyngeal and cervicopharyngeal weakness associated with areflexia in the upper limb. Here, we are describing a case of a 20-year-old female who had a preceding history of fever with thrombocytopenia that was found to be dengue ELISA positive. This was followed by rapidly progressive weakness of cervical, bulbar, and bilateral facial muscles along with areflexia of upper limb. Nerve conduction study showed a reduced compound muscle action potential amplitude in the upper limb, and the CSF examination showed albuminocytological dissociation. The patient was given intravenous immunoglobulin, and she started improving within 3 days of commencing the treatment.
咽-颈-臂（PCB）变异型是格林-巴利综合征的一种罕见局限性变异型，表现为迅速进展的口咽和颈咽肌无力，并伴有上肢腱反射消失。在此，我们描述一例20岁女性病例，该患者先前有发热伴血小板减少病史，登革热酶联免疫吸附测定（ELISA）呈阳性。随后出现颈部、延髓和双侧面部肌肉迅速进展性无力，以及上肢腱反射消失。神经传导研究显示上肢复合肌肉动作电位幅度降低，脑脊液检查显示蛋白细胞分离。给予患者静脉注射免疫球蛋白，治疗开始后3天内病情开始改善。
