B细胞急性淋巴细胞白血病以面部浸润性斑块形式的早熟表现。
A Precocious Presentation of B-cell Acute Lymphoblastic Leukemia as Infiltrated Plaques on the Face.
作者信息
Cotter David G, Hinds Brian R, Orme Charisse
机构信息
Dermatology, Univeristy of California San Diego, San Diego, USA.
Dermatology, University of California San Diego, San Diego, USA.
出版信息
Cureus. 2019 Feb 5;11(2):e4021. doi: 10.7759/cureus.4021.
Leukemia cutis, or infiltration of leukemic cells into the skin, occurs rarely in B-cell acute lymphocytic leukemia (ALL). Herein, we have described a rare, precocious presentation of B-cell ALL presenting as indurated facial plaques in a 69-year-old man. Biopsy of the facial plaques revealed precursor B-cell leukemia/lymphoma in the skin and prompted urgent hematologic-oncologic evaluation. Bone marrow biopsy yielded a final diagnosis of B-cell ALL. The patient underwent induction therapy, and at the last available follow-up, a matched unrelated donor transplant was planned.
皮肤白血病，即白血病细胞浸润皮肤，在B细胞急性淋巴细胞白血病（ALL）中很少见。在此，我们描述了一名69岁男性罕见的、早熟的B细胞ALL表现为面部硬结性斑块。面部斑块活检显示皮肤中有前体B细胞白血病/淋巴瘤，并促使进行紧急血液肿瘤学评估。骨髓活检最终诊断为B细胞ALL。患者接受了诱导治疗，在最后一次随访时，计划进行匹配的无关供体移植。
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