Bookstein J J, Valji K, Parsons L, Kessler W
J Urol. 1987 Feb;137(2):333-7. doi: 10.1016/s0022-5347(17)44017-1.
Progress in diagnosis and therapy of impotence is handicapped by the absence of a validated and objective method for evaluating the vascular system; a gold-standard for vasculogenic impotence is needed. Prior experience has indicated that conventional arteriography in unanesthetized patients is unreliable in evaluation of the penile arterial supply. We have improved our arteriographic methods by the routine application of selective pudendal injections, vasodilation pharmacoangiography with nitroglycerin and papaverine, and direct magnification. Experience in 37 impotent patients demonstrates marked improvement in the quality of visualization of distal vessels, and the frequent presence of functional vasoconstriction of medium and small arteries that can be distinguished from organic disease only with vasodilators. We believe these angiographic methods will improve the criteria against which other diagnostic and therapeutic methods can be objectively assessed.
阳痿诊断与治疗的进展因缺乏一种经过验证的客观评估血管系统的方法而受到阻碍;需要一种血管性阳痿的金标准。既往经验表明,未麻醉患者的传统动脉造影在评估阴茎动脉供血方面并不可靠。我们通过常规应用选择性阴部注射、硝酸甘油和罂粟碱的血管扩张药物血管造影以及直接放大技术改进了动脉造影方法。对37例阳痿患者的经验表明,远端血管的可视化质量有了显著改善,并且经常出现中小动脉的功能性血管收缩,只有使用血管扩张剂才能将其与器质性疾病区分开来。我们相信这些血管造影方法将改进其他诊断和治疗方法可据以进行客观评估的标准。