缺血性和出血性中风后的上肢恢复:SALGOT研究的一部分。

Upper extremity recovery after ischaemic and haemorrhagic stroke: Part of the SALGOT study.

作者信息

Persson Hanna C, Opheim Arve, Lundgren-Nilsson Åsa, Alt Murphy Margit, Danielsson Anna, Sunnerhagen Katharina S

机构信息

Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden.

Sunnaas Rehabilitation Hospital, Nesoddtangen, Norway.

出版信息

Eur Stroke J. 2016 Dec;1(4):310-319. doi: 10.1177/2396987316672809. Epub 2016 Oct 17.

Abstract

INTRODUCTION

The purpose was to explore if there are differences in extent of change in upper extremity motor function and activity capacity, in persons with ischaemic versus haemorrhagic stroke, during the first year post stroke.

PATIENTS AND METHODS

One hundred seventeen persons with stroke (ischaemic  = 98, haemorrhagic  = 19) and reduced upper extremity function 3 days after onset were consecutively included to the Stroke Arm Longitudinal Study at the University of Gothenburg (SALGOT) from a stroke unit. Upper extremity motor function (Fugl-Meyer Assessment Scale for Upper Extremity (FMA-UE)) and activity capacity (Action Research Arm Test (ARAT)) were assessed at 6 assessments during the first year; age and initial stroke severity were recorded. Differences between groups in extent of change over time of upper extremity motor function and activity capacity were analysed with mixed models repeated measurements method.

RESULTS

Significant improvements were found in function and activity in both groups within the first month ( = 0.001). Higher age and more severe stroke had a negative impact on recovery in both groups. Larger improvements of function and activity were seen in haemorrhagic stroke compared to ischaemic, both from 3 days to 3- and 12 months, and from 1 month to 3 months. Both groups reached similar levels of function and activity at 3 months post stroke.

CONCLUSION

Although persons with haemorrhagic stroke had initially lower scores than those with ischaemic stroke, they had a larger improvement within the first 3 months, and thereafter both groups had similar function and activity.

摘要

引言

目的是探讨缺血性中风与出血性中风患者在中风后第一年上肢运动功能和活动能力的变化程度是否存在差异。

患者与方法

117名中风患者(缺血性中风98例,出血性中风19例)在发病3天后上肢功能减退,从一家中风单元连续纳入哥德堡大学的中风手臂纵向研究(SALGOT)。在第一年进行6次评估时,评估上肢运动功能(上肢Fugl-Meyer评估量表(FMA-UE))和活动能力(动作研究手臂测试(ARAT));记录年龄和初始中风严重程度。采用混合模型重复测量方法分析两组上肢运动功能和活动能力随时间变化程度的差异。

结果

两组在第一个月内功能和活动均有显著改善(P = 0.001)。年龄较大和中风较严重对两组的恢复均有负面影响。与缺血性中风相比,出血性中风在从3天到3个月和12个月,以及从1个月到3个月期间,功能和活动的改善更大。两组在中风后3个月时达到相似的功能和活动水平。

结论

尽管出血性中风患者最初的分数低于缺血性中风患者,但他们在最初3个月内改善更大,此后两组的功能和活动相似。

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